Regional anesthesia in neonates with cleft lip and palate:
Retrospective study

J 2024

Regional anesthesia in neonates with cleft lip and palate: Retrospective study

RICHTROVÁ, Michaela, Olga KOŠKOVÁ, Martin JANKŮ, Tereza BÖNISCHOVÁ, Dominik FABIÁN et. al.

Basic information

Original name

Regional anesthesia in neonates with cleft lip and palate: Retrospective study

Authors

RICHTROVÁ, Michaela (203 Czech Republic, guarantor, belonging to the institution), Olga KOŠKOVÁ (203 Czech Republic, belonging to the institution), Martin JANKŮ (203 Czech Republic, belonging to the institution), Tereza BÖNISCHOVÁ (203 Czech Republic, belonging to the institution), Dominik FABIÁN (203 Czech Republic, belonging to the institution) and Petr ŠTOURAČ (203 Czech Republic, belonging to the institution)

Edition

International journal of pediatric otorhinolaryngology, Clare, Elsevier, 2024, 0165-5876

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30223 Anaesthesiology

Country of publisher

Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 1.500 in 2022

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1016/j.ijporl.2024.111965

UT WoS

001240156800001

Keywords in English

Cleft lip; Neonatal cleft lip surgery; Opioids in neonates; Infraorbital nerve block; Regional anesthesia

Abstract

V originále

Background: Orofacial clefts are the most common congenital abnormalities. Cleft lip reconstruction is performed mostly in 3 months of life including the neonatal period. The consumption of opioids during anesthesia is one of the monitored parameters of anesthesia safety. We investigated the effect of using an infraorbital nerve block for reducing opioid consumption during cleft lip surgery in neonates. Patients/methods: Overall, 100 patients who underwent primary cleft lip surgery in neonatal age between 2018 and 2021 were included in the study. The primary outcome was to compare opioid requirements during cleft lip surgery with and without using regional anesthesia. Secondary outcomes included a first oral intake from surgery between neonates with and without regional anesthesia and complications rate of infraorbital nerve block. Results: Data from 100 patients (46 patients with and 64 without regional anesthesia) were retrospectively analyzed and classified into two groups according to whether regional anesthesia during neonatal cleft lip surgery had been performed or not. The use of infraorbital block was found to be positively correlated with lower doses of opioids used during the general anesthesia for the surgery (mean 0.48 mu g/kg vs 0.29 mu g/kg, p < 0.05). The postoperative course was evaluated based on the interval from surgery to first oral intake which was statistically insignificant shorter (p = 0.16) in the group of patients using regional anesthesia. No complications were recorded in the group of patients with regional anesthesia. Conclusions: Regional anesthesia is associated with reduced opioid consumption during anesthesia thereby increasing the safety of anesthesia in neonates.

Links

MUNI/A/1109/2022, interní kód MU

Name: Hloubka anestezie: prospektivní observační studie

Investor: Masaryk University, The Depth of Paediatric Anaesthesia: Observational Trial

NU23-06-00301, research and development project

Name: Využití moderních technologií v individualizovaném přístupu k operačnímu řešení rozštěpových vad obličeje u dětských pacientů

Investor: Ministry of Health of the CR, Use of modern technology for individualized anesthesiologic management in pediatric patients with orofacial cleft malformation

Citovat

RICHTROVÁ, Michaela, Olga KOŠKOVÁ, Martin JANKŮ, Tereza BÖNISCHOVÁ, Dominik FABIÁN and Petr ŠTOURAČ. Regional anesthesia in neonates with cleft lip and palate: Retrospective study. International journal of pediatric otorhinolaryngology. Clare: Elsevier, 2024, vol. 180, May 2024, p. 1-5. ISSN 0165-5876. Available from: https://dx.doi.org/10.1016/j.ijporl.2024.111965.

@article{2417681,
   author = {Richtrová, Michaela and Košková, Olga and Janků, Martin and Bönischová, Tereza and Fabián, Dominik and Štourač, Petr},
   article_location = {Clare},
   article_number = {May 2024},
   doi = {http://dx.doi.org/10.1016/j.ijporl.2024.111965},
   keywords = {Cleft lip; Neonatal cleft lip surgery; Opioids in neonates; Infraorbital nerve block; Regional anesthesia},
   language = {eng},
   issn = {0165-5876},
   journal = {International journal of pediatric otorhinolaryngology},
   title = {Regional anesthesia in neonates with cleft lip and palate: Retrospective study},
   url = {https://www.sciencedirect.com/science/article/pii/S0165587624001198?via%3Dihub},
   volume = {180},
   year = {2024}
}

TY  - JOUR
ID  - 2417681
AU  - Richtrová, Michaela - Košková, Olga - Janků, Martin - Bönischová, Tereza - Fabián, Dominik - Štourač, Petr
PY  - 2024
TI  - Regional anesthesia in neonates with cleft lip and palate: Retrospective study
JF  - International journal of pediatric otorhinolaryngology
VL  - 180
IS  - May 2024
SP  - 1-5
EP  - 1-5
PB  - Elsevier
SN  - 01655876
KW  - Cleft lip
KW  - Neonatal cleft lip surgery
KW  - Opioids in neonates
KW  - Infraorbital nerve block
KW  - Regional anesthesia
UR  - https://www.sciencedirect.com/science/article/pii/S0165587624001198?via%3Dihub
N2  - Background: Orofacial clefts are the most common congenital abnormalities. Cleft lip reconstruction is performed mostly in 3 months of life including the neonatal period. The consumption of opioids during anesthesia is one of the monitored parameters of anesthesia safety. We investigated the effect of using an infraorbital nerve block for reducing opioid consumption during cleft lip surgery in neonates. Patients/methods: Overall, 100 patients who underwent primary cleft lip surgery in neonatal age between 2018 and 2021 were included in the study. The primary outcome was to compare opioid requirements during cleft lip surgery with and without using regional anesthesia. Secondary outcomes included a first oral intake from surgery between neonates with and without regional anesthesia and complications rate of infraorbital nerve block. Results: Data from 100 patients (46 patients with and 64 without regional anesthesia) were retrospectively analyzed and classified into two groups according to whether regional anesthesia during neonatal cleft lip surgery had been performed or not. The use of infraorbital block was found to be positively correlated with lower doses of opioids used during the general anesthesia for the surgery (mean 0.48 mu g/kg vs 0.29 mu g/kg, p < 0.05). The postoperative course was evaluated based on the interval from surgery to first oral intake which was statistically insignificant shorter (p = 0.16) in the group of patients using regional anesthesia. No complications were recorded in the group of patients with regional anesthesia. Conclusions: Regional anesthesia is associated with reduced opioid consumption during anesthesia thereby increasing the safety of anesthesia in neonates.
ER  -

RICHTROVÁ, Michaela, Olga KOŠKOVÁ, Martin JANKŮ, Tereza BÖNISCHOVÁ, Dominik FABIÁN and Petr ŠTOURAČ. Regional anesthesia in neonates with cleft lip and palate: Retrospective study. \textit{International journal of pediatric otorhinolaryngology}. Clare: Elsevier, 2024, vol.~180, May 2024, p.~1-5. ISSN~0165-5876. Available from: https://dx.doi.org/10.1016/j.ijporl.2024.111965.

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