RICHTROVÁ, Michaela, Olga KOŠKOVÁ, Martin JANKŮ, Tereza BÖNISCHOVÁ, Dominik FABIÁN and Petr ŠTOURAČ. Regional anesthesia in neonates with cleft lip and palate: Retrospective study. International journal of pediatric otorhinolaryngology. Clare: Elsevier, 2024, vol. 180, May 2024, p. 1-5. ISSN 0165-5876. Available from: https://dx.doi.org/10.1016/j.ijporl.2024.111965.
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Basic information
Original name Regional anesthesia in neonates with cleft lip and palate: Retrospective study
Authors RICHTROVÁ, Michaela (203 Czech Republic, guarantor, belonging to the institution), Olga KOŠKOVÁ (203 Czech Republic, belonging to the institution), Martin JANKŮ (203 Czech Republic, belonging to the institution), Tereza BÖNISCHOVÁ (203 Czech Republic, belonging to the institution), Dominik FABIÁN (203 Czech Republic, belonging to the institution) and Petr ŠTOURAČ (203 Czech Republic, belonging to the institution).
Edition International journal of pediatric otorhinolaryngology, Clare, Elsevier, 2024, 0165-5876.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30223 Anaesthesiology
Country of publisher Ireland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 1.500 in 2022
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1016/j.ijporl.2024.111965
UT WoS 001240156800001
Keywords in English Cleft lip; Neonatal cleft lip surgery; Opioids in neonates; Infraorbital nerve block; Regional anesthesia
Tags 14110229, 14110322, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 9/7/2024 13:28.
Abstract
Background: Orofacial clefts are the most common congenital abnormalities. Cleft lip reconstruction is performed mostly in 3 months of life including the neonatal period. The consumption of opioids during anesthesia is one of the monitored parameters of anesthesia safety. We investigated the effect of using an infraorbital nerve block for reducing opioid consumption during cleft lip surgery in neonates. Patients/methods: Overall, 100 patients who underwent primary cleft lip surgery in neonatal age between 2018 and 2021 were included in the study. The primary outcome was to compare opioid requirements during cleft lip surgery with and without using regional anesthesia. Secondary outcomes included a first oral intake from surgery between neonates with and without regional anesthesia and complications rate of infraorbital nerve block. Results: Data from 100 patients (46 patients with and 64 without regional anesthesia) were retrospectively analyzed and classified into two groups according to whether regional anesthesia during neonatal cleft lip surgery had been performed or not. The use of infraorbital block was found to be positively correlated with lower doses of opioids used during the general anesthesia for the surgery (mean 0.48 mu g/kg vs 0.29 mu g/kg, p < 0.05). The postoperative course was evaluated based on the interval from surgery to first oral intake which was statistically insignificant shorter (p = 0.16) in the group of patients using regional anesthesia. No complications were recorded in the group of patients with regional anesthesia. Conclusions: Regional anesthesia is associated with reduced opioid consumption during anesthesia thereby increasing the safety of anesthesia in neonates.
Links
MUNI/A/1109/2022, interní kód MUName: Hloubka anestezie: prospektivní observační studie
Investor: Masaryk University, The Depth of Paediatric Anaesthesia: Observational Trial
NU23-06-00301, research and development projectName: Využití moderních technologií v individualizovaném přístupu k operačnímu řešení rozštěpových vad obličeje u dětských pacientů
Investor: Ministry of Health of the CR, Use of modern technology for individualized anesthesiologic management in pediatric patients with orofacial cleft malformation
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