J 2022

Effect of cerebral microbleeds on hemorrhagic transformation and functional prognosis after intravenous thrombolysis of cerebral infarction

CHEN, Jinli, Kamil ĎURIŠ and Xiaobo YANG

Basic information

Original name

Effect of cerebral microbleeds on hemorrhagic transformation and functional prognosis after intravenous thrombolysis of cerebral infarction

Authors

CHEN, Jinli, Kamil ĎURIŠ (203 Czech Republic, belonging to the institution) and Xiaobo YANG

Edition

Brain Hemorrhages, BEIJING, KeAi Communications Co. 2022, 2589-238X

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30210 Clinical neurology

Country of publisher

China

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Organization unit

Faculty of Medicine

UT WoS

001128690900001

Keywords in English

Cerebral microbleeds; Intravenous thrombolysis; Hemorrhagic transformation

Tags

International impact, Reviewed
Změněno: 11/7/2024 09:09, Mgr. Tereza Miškechová

Abstract

V originále

Hemorrhagic transformation is a common complication of acute cerebral infarction, and rtPA thrombolytic therapy will increase the risk of hemorrhagic transformation. Cerebral microbleeds (CMBs) have become an important and independent predictor of cerebral hemorrhage. However, it is still controversial whether CMBs increase the risk of intracranial hemorrhage (ICH) and poor prognosis (PFO) after intra-venous thrombolysis (IVT) in patients with acute ischemic stroke (AIS).This review summarizes a number of studies on microbleeds in clinical patients, and discusses whether the presence, number, and distribution of CMBs are related to ICH and PFO after IVT in AIS patients, as well as the significance of CMBs in IVT decision-making in AIS.(c) 2022 International Hemorrhagic Stroke Association. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd. This is an open access article under the CC BY-NC-ND license (http://creati-vecommons.org/licenses/by-nc-nd/4.0/).