Neural bases of social deficits in ADHD: A systematic review.
Does the Theory of Mind matter?

J 2024

Neural bases of social deficits in ADHD: A systematic review. Does the Theory of Mind matter?

NOVAK, Lukas, Klara MALINAKOVA, Radek TRNKA, Petr MIKOSKA, Tomáš SVĚRÁK et. al.

Basic information

Original name

Neural bases of social deficits in ADHD: A systematic review. Does the Theory of Mind matter?

Authors

NOVAK, Lukas (203 Czech Republic), Klara MALINAKOVA (203 Czech Republic), Radek TRNKA (203 Czech Republic), Petr MIKOSKA (203 Czech Republic), Tomáš SVĚRÁK (203 Czech Republic, belonging to the institution), Hanni KIISKI, Peter TAVEL (203 Czech Republic) and Jitse P. VAN DIJK

Edition

Brain Research Bulletin, OXFORD, PERGAMON-ELSEVIER SCIENCE LTD, 2024, 0361-9230

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30103 Neurosciences

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 3.800 in 2022

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1016/j.brainresbull.2024.111011

UT WoS

001261379900001

Keywords in English

ADHD; Mentalization; FMRI; Children; Neural correlates; Neural networks

Abstract

V originále

Introduction: The Attention Deficit Hyperactivity Disorder (ADHD) causes serious interpersonal problems from childhood to adulthood, one of them being problematic social functioning. This phenomenon in ADHD should be associated with impairments in the Theory of Mind (ToM). Therefore, understanding the neural correlates of the ToM could be crucial for helping individuals with ADHD with their social functioning. Thus, we aimed to review published literature concerning neuroanatomical and functional correlates of ToM deficits in children and adolescents with ADHD. Methods: We reviewed studies published between 1970 and 2023. In accordance with PRISMA guidelines, after data from three databases were collected, two authors (LN and PM) independently screened all relevant records (n=638) and consequently, both authors did the data extraction. The quality of the included studies (n=5) was measured by a modified version of The Newcastle-Ottawa Scale and by measures specific for our study. This systematic review was registered on PROSPERO (CRD42020139847). Results: Results indicated that impairments in performing of the ToM tasks were negatively associated with the grey matter volume in the bilateral amygdala and hippocampus in both, ADHD and control group. In EEG studies, a significantly greater electrophysiological activity during ToM tasks was observed in the, frontal, temporal, parietal and occipital lobes in participants with ADHD as compared to healthy subjects. Conclusion: More research is needed to explore the ToM deficits in children with ADHD. Future research might focus on the neural circuits associated with attention and inhibition, which deficits seems to contribute to the ToM deficits in children and adolescents with ADHD.

Citovat

NOVAK, Lukas, Klara MALINAKOVA, Radek TRNKA, Petr MIKOSKA, Tomáš SVĚRÁK, Hanni KIISKI, Peter TAVEL and Jitse P. VAN DIJK. Neural bases of social deficits in ADHD: A systematic review. Does the Theory of Mind matter? Brain Research Bulletin. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD, 2024, vol. 215, September 2024, p. 1-10. ISSN 0361-9230. Available from: https://dx.doi.org/10.1016/j.brainresbull.2024.111011.

@article{2418103,
   author = {Novak, Lukas and Malinakova, Klara and Trnka, Radek and Mikoska, Petr and Svěrák, Tomáš and Kiiski, Hanni and Tavel, Peter and van Dijk, Jitse P.},
   article_location = {OXFORD},
   article_number = {September 2024},
   doi = {http://dx.doi.org/10.1016/j.brainresbull.2024.111011},
   keywords = {ADHD; Mentalization; FMRI; Children; Neural correlates; Neural networks},
   language = {eng},
   issn = {0361-9230},
   journal = {Brain Research Bulletin},
   title = {Neural bases of social deficits in ADHD: A systematic review. Does the Theory of Mind matter?},
   url = {https://www.sciencedirect.com/science/article/pii/S0361923024001448?via%3Dihub},
   volume = {215},
   year = {2024}
}

TY  - JOUR
ID  - 2418103
AU  - Novak, Lukas - Malinakova, Klara - Trnka, Radek - Mikoska, Petr - Svěrák, Tomáš - Kiiski, Hanni - Tavel, Peter - van Dijk, Jitse P.
PY  - 2024
TI  - Neural bases of social deficits in ADHD: A systematic review. Does the Theory of Mind matter?
JF  - Brain Research Bulletin
VL  - 215
IS  - September 2024
SP  - 1-10
EP  - 1-10
PB  - PERGAMON-ELSEVIER SCIENCE LTD
SN  - 03619230
KW  - ADHD
KW  - Mentalization
KW  - FMRI
KW  - Children
KW  - Neural correlates
KW  - Neural networks
UR  - https://www.sciencedirect.com/science/article/pii/S0361923024001448?via%3Dihub
N2  - Introduction: The Attention Deficit Hyperactivity Disorder (ADHD) causes serious interpersonal problems from childhood to adulthood, one of them being problematic social functioning. This phenomenon in ADHD should be associated with impairments in the Theory of Mind (ToM). Therefore, understanding the neural correlates of the ToM could be crucial for helping individuals with ADHD with their social functioning. Thus, we aimed to review published literature concerning neuroanatomical and functional correlates of ToM deficits in children and adolescents with ADHD. Methods: We reviewed studies published between 1970 and 2023. In accordance with PRISMA guidelines, after data from three databases were collected, two authors (LN and PM) independently screened all relevant records (n=638) and consequently, both authors did the data extraction. The quality of the included studies (n=5) was measured by a modified version of The Newcastle-Ottawa Scale and by measures specific for our study. This systematic review was registered on PROSPERO (CRD42020139847). Results: Results indicated that impairments in performing of the ToM tasks were negatively associated with the grey matter volume in the bilateral amygdala and hippocampus in both, ADHD and control group. In EEG studies, a significantly greater electrophysiological activity during ToM tasks was observed in the, frontal, temporal, parietal and occipital lobes in participants with ADHD as compared to healthy subjects. Conclusion: More research is needed to explore the ToM deficits in children with ADHD. Future research might focus on the neural circuits associated with attention and inhibition, which deficits seems to contribute to the ToM deficits in children and adolescents with ADHD.
ER  -

NOVAK, Lukas, Klara MALINAKOVA, Radek TRNKA, Petr MIKOSKA, Tomáš SVĚRÁK, Hanni KIISKI, Peter TAVEL and Jitse P. VAN DIJK. Neural bases of social deficits in ADHD: A systematic review. Does the Theory of Mind matter? \textit{Brain Research Bulletin}. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD, 2024, vol.~215, September 2024, p.~1-10. ISSN~0361-9230. Available from: https://dx.doi.org/10.1016/j.brainresbull.2024.111011.

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