Socioeconomic status and adiposity in childhood cancer survivors: A cross-sectional retrospective study

ŠTRUBLOVÁ, Lucie, Tomáš KEPÁK, Kateřina KEPÁKOVÁ, Marta HOLÍKOVÁ, Filip ZLÁMAL, Daniela KURUCZOVÁ, Jaroslav ŠTĚRBA and Julie BIENERTOVÁ-VAŠKŮ. Socioeconomic status and adiposity in childhood cancer survivors: A cross-sectional retrospective study. In 3rd International Symposium on Late Complications after Childhood Cancer (ISLCCC) 2024. 2024.

Basic information

• Original name: Socioeconomic status and adiposity in childhood cancer survivors: A cross-sectional retrospective study
• Authors: ŠTRUBLOVÁ, Lucie (203 Czech Republic, guarantor, belonging to the institution), Tomáš KEPÁK (203 Czech Republic), Kateřina KEPÁKOVÁ (203 Czech Republic), Marta HOLÍKOVÁ (203 Czech Republic), Filip ZLÁMAL (203 Czech Republic), Daniela KURUCZOVÁ (703 Slovakia), Jaroslav ŠTĚRBA (203 Czech Republic) and Julie BIENERTOVÁ-VAŠKŮ (203 Czech Republic).
• Edition: 3rd International Symposium on Late Complications after Childhood Cancer (ISLCCC) 2024, 2024.

Other information

• Original language: English
• Type of outcome: Conference abstract
• Field of Study: 30304 Public and environmental health
• Confidentiality degree: is not subject to a state or trade secret
• WWW: URL
• Organization unit: Faculty of Medicine
• Keywords in English: late effects of childhood cancer unemployment adiposity socioeconomic status cancer survivorship

Abstract

Background/Purpose: This is a retrospective cross-sectional study examining the association between unemployment, cancer type, treatment and total body fat percentage of childhood cancer survivors recruited at St. Anne’s University Hospital in Brno, Czech Republic. Methods: A total of 55 survivors aged 18-49 who were in remission of cancer and fulfilled the criteria for body composition measurements by the BIA and completed questionnaires investigating their socioeconomic status, employment status, and history. Results: There was a significant relationship between the employment status and central nervous system-directed treatment ( χ2(1)=7.53, p=0.006, Cramér’s V=0.38) and between the type of cancer and employment status (χ2(3)=7.83, p=0.049, Cramér’s V=0.38), the highest unemployment rate was recorded for brain and spine survivors (72.7%) compared to survivors with other diagnosis (35.7%) (uLR(1)=4.91, p=0.027; OR=4.80, 95% CI:1.10-20.86, p=0.036); these survivors did not have a significantly different body fat percentage compared to survivors with other diagnoses (t(53)=1.29, p=0.202, Cohen’s d=0.41) Interestingly, the survivors reporting having a partner also had a significantly higher percentage of body fat (t(53)=2.90, p=0.005, Cohen’s d=0.81). A linear regression model was used to model the percentage of body fat in relation to a set of selected variables and the we observed a significant effect of sex (female vs male: b=6.37, 95% CI: 1.82- 10.93, p=0.007), partnership status (yes vs no: b=5.65, 95% CI: 0.67-10.62, p=0.027) and category of diagnosis (Brain and spinal column tumors vs Other solid tumors: b=12.40, 95% CI: 0.59-24.21, p=0.040 ; Brain and spinal column tumors vs Lymphoma: b=14.02, 95% CI: 2.06-25.97, p=0.023). Conclusion: Employment status and risk of adiposity in childhood cancer survivors depends on the type of treatment and diagnosis group, which may significantly impact their lifestyle and overall quality of life after treatment.

Links

• MUNI/A/1391/2021, interní kód MU: Name: Molekulární, buněčná, tkáňová a systémová patofyziologie vybraných komplexních nemocí (Acronym: KOMPLEX_PF)

Investor: Masaryk University