The importance of multimodal CT examination in stroke mimics diagnosis: design of prospective ...

@article{2418740,
   author = {Dvornikova, Katerina and Kunesova, Veronika and Ely, Marcela and Ostry, Svatopluk and Cabal, Martin and Reiser, Martin and Machova, Linda and Pavlinova, Marketa and Konde, Adela and Elias, Pavel and Jonszta, Tomas and Havelka, Jaroslav and Volny, Ondrej and Bar, Michal},
   article_location = {Lausanne},
   article_number = {15},
   doi = {http://dx.doi.org/10.3389/fneur.2024.1365986},
   keywords = {CT perfusion; multimodal CT; stroke; stroke mimics; MRI},
   language = {eng},
   issn = {1664-2295},
   journal = {Frontiers in Neurology},
   title = {The importance of multimodal CT examination in stroke mimics diagnosis: design of prospective observational multicentre study},
   url = {https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2024.1365986/full},
   volume = {15},
   year = {2024}
}

TY  - JOUR
ID  - 2418740
AU  - Dvornikova, Katerina - Kunesova, Veronika - Ely, Marcela - Ostry, Svatopluk - Cabal, Martin - Reiser, Martin - Machova, Linda - Pavlinova, Marketa - Konde, Adela - Elias, Pavel - Jonszta, Tomas - Havelka, Jaroslav - Volny, Ondrej - Bar, Michal
PY  - 2024
TI  - The importance of multimodal CT examination in stroke mimics diagnosis: design of prospective observational multicentre study
JF  - Frontiers in Neurology
VL  - 15
IS  - 15
SP  - 1-7
EP  - 1-7
PB  - Frontiers
SN  - 16642295
KW  - CT perfusion
KW  - multimodal CT
KW  - stroke
KW  - stroke mimics
KW  - MRI
UR  - https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2024.1365986/full
N2  - Introduction: Non-contrast computed tomography (CT) and CT angiography are the gold standard in neuroimaging diagnostics in the case of suspected stroke. CT perfusion (CTP) may play an important role in the diagnosis of stroke mimics (SM), but currently, it is not a standard part of the stroke diagnostic procedure. The project is a multicentre prospective observational clinical research focused on refining the diagnostics of stroke and stroke mimics (SM) in hospital care. Aim: This study aimed to evaluate the degree of specificity and sensitivity of multimodal CT (NCCT, CTA, and CTP) in the diagnosis of SM versus stroke. Methodology: In this study, we will include 3,000 patients consecutively admitted to the comprehensive stroke centres with a diagnosis of suspected stroke. On the basis of clinical parameters and the results of multimodal CT and magnetic resonance imaging (MRI), the diagnosis of stroke and SM will be established. To clarify the significance of the use of the multimodal CT scan, the analysis will include a comparison of the blinded results for each imaging scan performed by radiologists and AI technology and a comparison of the initial and final diagnosis of the enrolled patients. Based on our results, we will compare the economic indicators and costs that would be saved by not providing inadequate treatment to patients with SM. Conclusion: The expected outcome is to present an optimised diagnostic procedure that results in a faster and more accurate diagnosis, thereby eliminating the risk of inadequate treatment in patients with SM.
ER  - 

DVORNIKOVA, Katerina, Veronika KUNESOVA, Marcela ELY, Svatopluk OSTRY, Martin CABAL, Martin REISER, Linda MACHOVA, Marketa PAVLINOVA, Adela KONDE, Pavel ELIAS, Tomas JONSZTA, Jaroslav HAVELKA, Ondrej VOLNY and Michal BAR. The importance of multimodal CT examination in stroke mimics diagnosis: design of prospective observational multicentre study. \textit{Frontiers in Neurology}. Lausanne: Frontiers, 2024, vol.~15, No~15, p.~1-7. ISSN~1664-2295. Available from: https://dx.doi.org/10.3389/fneur.2024.1365986.