Other formats:
BibTeX
LaTeX
RIS
@article{2423119,
author = {Hogberg, Helena T. and Tsaioun, Katya and Breidenbach, Joshua D. and Elmore, Bekki and Filipovska, Julija and GarciaandReyero, Natalia and Hargreaves, Alan J. and Joshi, Ojasi and Omeragic, Elma and Plant, Shannon and Ram, Rebecca and Virmani, Ishita and Waspe, Jennifer and Macmillan, Donna S.},
article_location = {AMSTERDAM},
article_number = {July 2024},
doi = {http://dx.doi.org/10.1016/j.neuro.2024.05.003},
keywords = {COVID-19; SARS-CoV-2; Neurological; Literature screening; Scoping review},
language = {eng},
issn = {0161-813X},
journal = {NEUROTOXICOLOGY},
title = {A systematic scoping review of the neurological effects of COVID-19},
url = {https://www.sciencedirect.com/science/article/pii/S0161813X2400041X?via%3Dihub},
volume = {103},
year = {2024}
}
TY - JOUR
ID - 2423119
AU - Hogberg, Helena T. - Tsaioun, Katya - Breidenbach, Joshua D. - Elmore, Bekki - Filipovska, Julija - Garcia-Reyero, Natalia - Hargreaves, Alan J. - Joshi, Ojasi - Omeragic, Elma - Plant, Shannon - Ram, Rebecca - Virmani, Ishita - Waspe, Jennifer - Macmillan, Donna S.
PY - 2024
TI - A systematic scoping review of the neurological effects of COVID-19
JF - NEUROTOXICOLOGY
VL - 103
IS - July 2024
SP - 16-26
EP - 16-26
PB - ELSEVIER
SN - 0161813X
KW - COVID-19
KW - SARS-CoV-2
KW - Neurological
KW - Literature screening
KW - Scoping review
UR - https://www.sciencedirect.com/science/article/pii/S0161813X2400041X?via%3Dihub
N2 - Background: The global coronavirus 2019 (COVID-19) pandemic began in early 2020, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In mid -2020 the CIAO (Modelling the Pathogenesis of C OV E D -19 Using the Adverse Out come Pathway Framework) project was established, bringing together over 75 interdisciplinary scientists worldwide to collaboratively investigate the underlying biological mechanisms of COVID-19 and consolidate the data using the Adverse Outcome Pathway (AOP) Framework. Neurological symptoms such as anosmia and encephalitis have been frequently reported to be associated with infection with SARS-CoV-2. Objective: Within CIAO, a working group was formed to conduct a systematic scoping review of COVID-19 and its related neurological symptoms to determine which key events and modulating factors are most commonly reported and to identify knowledge gaps. Design: Lit COVID was used to retrieve 86,075 papers of which 10,244 contained relevant keywords. After title and abstract screening, 2,328 remained and their full texts were reviewed based on predefined inclusion and exclusion criteria. 991 studies fulfilled the inclusion criteria and were retrieved to conduct knowledge synthesis. Results: The majority of publications reported human observational studies. Early key events were less likely to be reported compared to middle and late key events/adverse outcomes. The majority of modulating factors described related to age or sex. Less recognised COVID-19 associated AO or neurological effects of COVID-19 were also identified including multiple sclerosis/demyelination, neurodegeneration/cognitive effects and peripheral neuronal effects. Conclusion: There were many methodological and reporting issues noted in the reviewed studies. In particular, publication abstracts would benefit from clearer reporting of the methods and endpoints used and the key findings, to ensure relevant papers are included when systematic reviews are conducted. The information extracted from the scoping review may be useful in understanding the mechanisms of neurological effects of COVID-19 and to further develop or support existing AOPs linking COVID-19 and its neurological key events and adverse outcomes. Further evaluation of the less recognised COVID-19 effects is needed.
ER -
HOGBERG, Helena T., Katya TSAIOUN, Joshua D. BREIDENBACH, Bekki ELMORE, Julija FILIPOVSKA, Natalia GARCIA-REYERO, Alan J. HARGREAVES, Ojasi JOSHI, Elma OMERAGIC, Shannon PLANT, Rebecca RAM, Ishita VIRMANI, Jennifer WASPE and Donna S. MACMILLAN. A systematic scoping review of the neurological effects of COVID-19. \textit{NEUROTOXICOLOGY}. AMSTERDAM: ELSEVIER, 2024, vol.~103, July 2024, p.~16-26. ISSN~0161-813X. Available from: https://dx.doi.org/10.1016/j.neuro.2024.05.003.
|
