J 2024

Adherence to the ISHLT Protocol for the Referral of Patients with Idiopathic Pulmonary Fibrosis to the Transplantation Center among of Czech Centers for Interstitial Lung Diseases

STERCLOVA, Martina, Martina DOUBKOVÁ, Lubica SÝKOROVÁ, Vladimir BARTOS, Monika ZURKOVA et. al.

Basic information

Original name

Adherence to the ISHLT Protocol for the Referral of Patients with Idiopathic Pulmonary Fibrosis to the Transplantation Center among of Czech Centers for Interstitial Lung Diseases

Authors

STERCLOVA, Martina (203 Czech Republic), Martina DOUBKOVÁ (203 Czech Republic), Lubica SÝKOROVÁ (703 Slovakia), Vladimir BARTOS (203 Czech Republic), Monika ZURKOVA (203 Czech Republic), Vladimira LOSTAKOVA (203 Czech Republic), Radka MOKOSOVA (203 Czech Republic), Martina PLACKOVA (203 Czech Republic), Ladislav LACINA (203 Czech Republic), Michaela CIMROVA (203 Czech Republic), Radka BITTENGLOVA (203 Czech Republic), Pavlina LISA (203 Czech Republic), Pavla MUSILOVA (203 Czech Republic), Daniel DOLEZAL (203 Czech Republic), Jana PSIKALOVA (203 Czech Republic), Petra OVESNÁ (203 Czech Republic, belonging to the institution) and Martina VASAKOVA KOZIAR (203 Czech Republic)

Edition

PULMONARY MEDICINE, LONDON, HINDAWI LTD, 2024, 2090-1836

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30203 Respiratory systems

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 4.300 in 2022

Organization unit

Faculty of Medicine

UT WoS

001264811300001

Keywords in English

Idiopathic Pulmonary Fibrosis; ISHLT Protocol

Tags

Tags

International impact, Reviewed
Změněno: 15/8/2024 10:32, Mgr. Tereza Miškechová

Abstract

V originále

There are limited data on referral rates and the number of patients with idiopathic pulmonary fibrosis (IPF) who are eligible for lung transplantation. The aim of the present study was to assess adherence to the consensus of the International Society for Heart and Lung Transplantation (ISHLT) for the referral of patients with IPF among Czech interstitial lung disease (ILD) centers. Czech patients who were diagnosed with IPF between 1999 and 2021 (n=1584) and who were less than 65 years old at the time of diagnosis were retrospectively selected from the Czech Republic of the European Multipartner Idiopathic Pulmonary Fibrosis Registry (EMPIRE). Nonsmokers and ex-smokers with a body mass index (BMI) of <32 kg/m2 (n=404) were included for further analyses. Patients with a history of cancer <5 years from the time of IPF diagnosis, patients with alcohol abuse, and patients with an accumulation of vascular comorbidities were excluded. The trajectory of individual patients was verified at the relevant ILD center. From the database of transplant patients (1999-12/2021, n=541), all patients who underwent transplantation for pulmonary fibrosis (n=186) were selected, and the diagnosis of IPF was subsequently verified from the patient's medical records (n=67). A total of 304 IPF patients were eligible for lung transplantation. Ninety-six patients were referred to the transplant center, 50% (n=49) of whom were referred for lung transplantation. Thirty percent of potentially eligible patients not referred to the transplant center were considered to have too many comorbidities by the reporting physician, 19% of IPF patients denied lung transplantation, and 17% were not referred due to age. Among Czech patients with IPF, there may be a larger pool of potential lung transplant candidates than has been reported to the transplant center to date.