Global Impact of the COVID-19 Pandemic on Cerebral Venous
Thrombosis and Mortality (vol 24, pg 256, 2022)

J 2024

Global Impact of the COVID-19 Pandemic on Cerebral Venous Thrombosis and Mortality (vol 24, pg 256, 2022)

NGUYEN, Thanh N, Muhammad M QURESHI, Piers KLEIN, Hiroshi YAMAGAMI, Mohamad ABDALKADER et. al.

Basic information

Original name

Global Impact of the COVID-19 Pandemic on Cerebral Venous Thrombosis and Mortality (vol 24, pg 256, 2022)

Authors

NGUYEN, Thanh N, Muhammad M QURESHI, Piers KLEIN, Hiroshi YAMAGAMI, Mohamad ABDALKADER, Robert MIKULÍK (203 Czech Republic, belonging to the institution), Anvitha SATHYA, Ossama Yassin MANSOUR, Anna CZLONKOWSKA, Hannah LO, Thalia S FIELD, Andreas CHARIDIMOU, Soma BANERJEE, Shadi YAGHI, James E SIEGLER, Petra ŠEDOVÁ (203 Czech Republic, belonging to the institution), Joseph KWAN, de Sousa Diana AGUIAR, Jelle DEMEESTERE, Violiza INOA, Setareh Salehi OMRAN, Liqun ZHANG, Patrik MICHEL, Davide STRAMBO, Joao Pedro MARTO and Raul G NOGUEIRA

Edition

JOURNAL OF STROKE, SEOUL, KOREAN STROKE SOC, 2024, 2287-6391

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30210 Clinical neurology

Country of publisher

Republic of Korea

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 8.200 in 2022

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.5853/jos.2022.00752

UT WoS

001203679600005

Keywords in English

COVID-19; Cerebral venous thrombosis; Vaccine-induced immune thrombotic thrombocytopenia; Mortality; SARS-CoV-2; Stroke

Abstract

V originále

Background and Purpose Recent studies suggested an increased incidence of cerebral venous thrombosis (CVT) during the coronavirus disease 2019 (COVID-19) pandemic. We evaluated the volume of CVT hospitalization and in-hospital mortality during the 1st year of the COVID-19 pandemic compared to the preceding year. Methods We conducted a cross-sectional retrospective study of 171 stroke centers from 49 countries. We recorded COVID-19 admission volumes, CVT hospitalization, and CVT in-hospital mortality from January 1, 2019, to May 31, 2021. CVT diagnoses were identified by International Classification of Disease-10 (ICD-10) codes or stroke databases. We additionally sought to compare the same metrics in the first 5 months of 2021 compared to the corresponding months in 2019 and 2020 (ClinicalTrials.gov Identifier: NCT04934020). Results There were 2,313 CVT admissions across the 1-year pre-pandemic (2019) and pandemic year (2020); no differences in CVT volume or CVT mortality were observed. During the first 5 months of 2021, there was an increase in CVT volumes compared to 2019 (27.5%; 95% confidence interval [CI], 24.2 to 32.0; P<0.0001) and 2020 (41.4%; 95% CI, 37.0 to 46.0; P<0.0001). A COVID-19 diagnosis was present in 7.6% (132/1,738) of CVT hospitalizations. CVT was present in 0.04% (103/292,080) of COVID-19 hospitalizations. During the first pandemic year, CVT mortality was higher in patients who were COVID positive compared to COVID negative patients (8/53 [15.0%] vs. 41/910 [4.5%], P=0.004). There was an increase in CVT mortality during the first 5 months of pandemic years 2020 and 2021 compared to the first 5 months of the pre-pandemic year 2019 (2019 vs. 2020: 2.26% vs. 4.74%, P=0.05; 2019 vs. 2021: 2.26% vs. 4.99%, P=0.03). In the first 5 months of 2021, there were 26 cases of vaccine-induced immune thrombotic thrombocytopenia (VITT), resulting in six deaths. Conclusions During the 1st year of the COVID-19 pandemic, CVT hospitalization volume and CVT in-hospital mortality did not change compared to the prior year. COVID-19 diagnosis was associated with higher CVT in-hospital mortality. During the first 5 months of 2021, there was an increase in CVT hospitalization volume and increase in CVT-related mortality, partially attributable to VITT.

Links

LM2018128, research and development project

Name: Český národní uzel Evropské sítě infrastruktur klinického výzkumu (Acronym: CZECRIN)

Investor: Ministry of Education, Youth and Sports of the CR

Citovat

NGUYEN, Thanh N, Muhammad M QURESHI, Piers KLEIN, Hiroshi YAMAGAMI, Mohamad ABDALKADER, Robert MIKULÍK, Anvitha SATHYA, Ossama Yassin MANSOUR, Anna CZLONKOWSKA, Hannah LO, Thalia S FIELD, Andreas CHARIDIMOU, Soma BANERJEE, Shadi YAGHI, James E SIEGLER, Petra ŠEDOVÁ, Joseph KWAN, de Sousa Diana AGUIAR, Jelle DEMEESTERE, Violiza INOA, Setareh Salehi OMRAN, Liqun ZHANG, Patrik MICHEL, Davide STRAMBO, Joao Pedro MARTO and Raul G NOGUEIRA. Global Impact of the COVID-19 Pandemic on Cerebral Venous Thrombosis and Mortality (vol 24, pg 256, 2022). JOURNAL OF STROKE. SEOUL: KOREAN STROKE SOC, 2024, vol. 26, No 1, p. 129. ISSN 2287-6391. Available from: https://dx.doi.org/10.5853/jos.2022.00752.

@article{2423280,
   author = {Nguyen, Thanh N and Qureshi, Muhammad M and Klein, Piers and Yamagami, Hiroshi and Abdalkader, Mohamad and Mikulík, Robert and Sathya, Anvitha and Mansour, Ossama Yassin and Czlonkowska, Anna and Lo, Hannah and Field, Thalia S and Charidimou, Andreas and Banerjee, Soma and Yaghi, Shadi and Siegler, James E and Šedová, Petra and Kwan, Joseph and Aguiar, de Sousa Diana and Demeestere, Jelle and Inoa, Violiza and Omran, Setareh Salehi and Zhang, Liqun and Michel, Patrik and Strambo, Davide and Marto, Joao Pedro and Nogueira, Raul G},
   article_location = {SEOUL},
   article_number = {1},
   doi = {http://dx.doi.org/10.5853/jos.2022.00752},
   keywords = {COVID-19; Cerebral venous thrombosis; Vaccine-induced immune thrombotic thrombocytopenia; Mortality; SARS-CoV-2; Stroke},
   language = {eng},
   issn = {2287-6391},
   journal = {JOURNAL OF STROKE},
   title = {Global Impact of the COVID-19 Pandemic on Cerebral Venous Thrombosis and Mortality (vol 24, pg 256, 2022)},
   url = {https://j-stroke.org/journal/view.php?doi=10.5853/jos.2022.00752},
   volume = {26},
   year = {2024}
}

TY  - JOUR
ID  - 2423280
AU  - Nguyen, Thanh N - Qureshi, Muhammad M - Klein, Piers - Yamagami, Hiroshi - Abdalkader, Mohamad - Mikulík, Robert - Sathya, Anvitha - Mansour, Ossama Yassin - Czlonkowska, Anna - Lo, Hannah - Field, Thalia S - Charidimou, Andreas - Banerjee, Soma - Yaghi, Shadi - Siegler, James E - Šedová, Petra - Kwan, Joseph - Aguiar, de Sousa Diana - Demeestere, Jelle - Inoa, Violiza - Omran, Setareh Salehi - Zhang, Liqun - Michel, Patrik - Strambo, Davide - Marto, Joao Pedro - Nogueira, Raul G
PY  - 2024
TI  - Global Impact of the COVID-19 Pandemic on Cerebral Venous Thrombosis and Mortality (vol 24, pg 256, 2022)
JF  - JOURNAL OF STROKE
VL  - 26
IS  - 1
SP  - 129
EP  - 129
PB  - KOREAN STROKE SOC
SN  - 22876391
KW  - COVID-19
KW  - Cerebral venous thrombosis
KW  - Vaccine-induced immune thrombotic thrombocytopenia
KW  - Mortality
KW  - SARS-CoV-2
KW  - Stroke
UR  - https://j-stroke.org/journal/view.php?doi=10.5853/jos.2022.00752
N2  - Background and Purpose Recent studies suggested an increased incidence of cerebral venous thrombosis (CVT) during the coronavirus disease 2019 (COVID-19) pandemic. We evaluated the volume of CVT hospitalization and in-hospital mortality during the 1st year of the COVID-19 pandemic compared to the preceding year. Methods We conducted a cross-sectional retrospective study of 171 stroke centers from 49 countries. We recorded COVID-19 admission volumes, CVT hospitalization, and CVT in-hospital mortality from January 1, 2019, to May 31, 2021. CVT diagnoses were identified by International Classification of Disease-10 (ICD-10) codes or stroke databases. We additionally sought to compare the same metrics in the first 5 months of 2021 compared to the corresponding months in 2019 and 2020 (ClinicalTrials.gov Identifier: NCT04934020). Results There were 2,313 CVT admissions across the 1-year pre-pandemic (2019) and pandemic year (2020); no differences in CVT volume or CVT mortality were observed. During the first 5 months of 2021, there was an increase in CVT volumes compared to 2019 (27.5%; 95% confidence interval [CI], 24.2 to 32.0; P<0.0001) and 2020 (41.4%; 95% CI, 37.0 to 46.0; P<0.0001). A COVID-19 diagnosis was present in 7.6% (132/1,738) of CVT hospitalizations. CVT was present in 0.04% (103/292,080) of COVID-19 hospitalizations. During the first pandemic year, CVT mortality was higher in patients who were COVID positive compared to COVID negative patients (8/53 [15.0%] vs. 41/910 [4.5%], P=0.004). There was an increase in CVT mortality during the first 5 months of pandemic years 2020 and 2021 compared to the first 5 months of the pre-pandemic year 2019 (2019 vs. 2020: 2.26% vs. 4.74%, P=0.05; 2019 vs. 2021: 2.26% vs. 4.99%, P=0.03). In the first 5 months of 2021, there were 26 cases of vaccine-induced immune thrombotic thrombocytopenia (VITT), resulting in six deaths. Conclusions During the 1st year of the COVID-19 pandemic, CVT hospitalization volume and CVT in-hospital mortality did not change compared to the prior year. COVID-19 diagnosis was associated with higher CVT in-hospital mortality. During the first 5 months of 2021, there was an increase in CVT hospitalization volume and increase in CVT-related mortality, partially attributable to VITT.
ER  -

NGUYEN, Thanh N, Muhammad M QURESHI, Piers KLEIN, Hiroshi YAMAGAMI, Mohamad ABDALKADER, Robert MIKULÍK, Anvitha SATHYA, Ossama Yassin MANSOUR, Anna CZLONKOWSKA, Hannah LO, Thalia S FIELD, Andreas CHARIDIMOU, Soma BANERJEE, Shadi YAGHI, James E SIEGLER, Petra ŠEDOVÁ, Joseph KWAN, de Sousa Diana AGUIAR, Jelle DEMEESTERE, Violiza INOA, Setareh Salehi OMRAN, Liqun ZHANG, Patrik MICHEL, Davide STRAMBO, Joao Pedro MARTO and Raul G NOGUEIRA. Global Impact of the COVID-19 Pandemic on Cerebral Venous Thrombosis and Mortality (vol 24, pg 256, 2022). \textit{JOURNAL OF STROKE}. SEOUL: KOREAN STROKE SOC, 2024, vol.~26, No~1, p.~129. ISSN~2287-6391. Available from: https://dx.doi.org/10.5853/jos.2022.00752.

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