GOFUS, Jan, Jan VOJACEK, Mikita KARALKO, Pavel ZACEK, Adrian KOLESAR, Tomas TOPORCER, Martin URBAN, Filip GLAC, Stepan CERNY, Pavel HOMOLA, Jaroslav HLUBOCKY, Andrey SLAUTIN, Petr FILA, Daniela ŽÁKOVÁ, Jan ŠTĚRBA, Hiwad RASHID, Arnaud VAN LINDEN and Tomas HOLUBEC. Aortic valve performance after remodelling versus reimplantation in a propensity-matched comparison. EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY. CARY: OXFORD UNIV PRESS INC, 2024, vol. 66, No 2, p. 1-9. ISSN 1010-7940. Available from: https://dx.doi.org/10.1093/ejcts/ezae234.
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Basic information
Original name Aortic valve performance after remodelling versus reimplantation in a propensity-matched comparison
Authors GOFUS, Jan (203 Czech Republic), Jan VOJACEK (203 Czech Republic), Mikita KARALKO, Pavel ZACEK (203 Czech Republic), Adrian KOLESAR (203 Czech Republic), Tomas TOPORCER (203 Czech Republic), Martin URBAN (203 Czech Republic), Filip GLAC (203 Czech Republic), Stepan CERNY (203 Czech Republic), Pavel HOMOLA (203 Czech Republic), Jaroslav HLUBOCKY (203 Czech Republic), Andrey SLAUTIN, Petr FILA (203 Czech Republic, belonging to the institution), Daniela ŽÁKOVÁ (203 Czech Republic, belonging to the institution), Jan ŠTĚRBA (203 Czech Republic, belonging to the institution), Hiwad RASHID, Arnaud VAN LINDEN and Tomas HOLUBEC (203 Czech Republic).
Edition EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, CARY, OXFORD UNIV PRESS INC, 2024, 1010-7940.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30201 Cardiac and Cardiovascular systems
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 3.400 in 2022
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1093/ejcts/ezae234
UT WoS 001284515800001
Keywords in English Aortic valve repair; Valve-sparing root replacement; Aortic root aneurysm; Aortic regurgitation; Propensity-score matching
Tags 14110911, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 19/8/2024 08:28.
Abstract
OBJECTIVES: Both aortic root remodelling and aortic valve (AV) reimplantation have been used for valve-sparing root replacement in patients with aortic root aneurysm with or without aortic regurgitation. There is no clear evidence to support one technique over the another. This study aimed to compare remodelling with basal ring annuloplasty versus reimplantation on a multicentre level with the use of propensity-score matching. METHODS: This was a retrospective international multicentre study of patients undergoing remodelling or reimplantation between 2010 and 2021. Twenty-three preoperative covariates (including root dimensions and valve characteristics) were used for propensity-score matching. Perioperative outcomes were analysed along with longer-term freedom from AV reoperation/reintervention and other major valve-related events. RESULTS: Throughout the study period, 297 patients underwent remodelling and 281 had reimplantation. Using propensity-score matching, 112 pairs were selected and further compared. We did not find a statistically significant difference in perioperative outcomes between the matched groups. Patients after remodelling had significantly higher reintervention risk than after reimplantation over the median follow-up of 6 years (P = 0.016). The remodelling technique (P = 0.02), need for decalcification (P = 0.03) and degree of immediate postoperative AV regurgitation (P < 0.001) were defined as independent risk factors for later AV reintervention. After exclusion of patients with worse than mild AV regurgitation immediately after repair, both techniques functioned comparably (P = 0.089). CONCLUSIONS: AV reimplantation was associated with better valve function in longer-term postoperatively than remodelling. If optimal immediate repair outcome was achieved, both techniques provided comparable AV function.
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