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@article{2424065,
author = {Vaclavik, Daniel and Pakizer, David and Hrbac, Tomas and Roubec, Martin and Prochazka, Vaclav and Jonszta, Tomas and Herzig, Roman and Skoloudik, David},
article_location = {Basel},
article_number = {1},
doi = {http://dx.doi.org/10.3390/biomedicines12010013},
keywords = {carotid stenosis; carotid endarterectomy},
language = {eng},
issn = {2227-9059},
journal = {Biomedicines},
title = {Changes in Cognitive Functions after Carotid Endarterectomy and Carotid Stenting: A Decade-Apart Comparison},
url = {https://www.mdpi.com/2227-9059/12/1/13},
volume = {12},
year = {2024}
}
TY - JOUR
ID - 2424065
AU - Vaclavik, Daniel - Pakizer, David - Hrbac, Tomas - Roubec, Martin - Prochazka, Vaclav - Jonszta, Tomas - Herzig, Roman - Skoloudik, David
PY - 2024
TI - Changes in Cognitive Functions after Carotid Endarterectomy and Carotid Stenting: A Decade-Apart Comparison
JF - Biomedicines
VL - 12
IS - 1
SP - 1-11
EP - 1-11
PB - MDPI
SN - 22279059
KW - carotid stenosis
KW - carotid endarterectomy
UR - https://www.mdpi.com/2227-9059/12/1/13
N2 - Background: This study investigates changes in cognitive function in patients with severe carotid stenosis who underwent carotid endarterectomy (CEA) and carotid stenting (CAS) over two decades. Methods: We compared cognitive function within 30 days after the procedure in 267 patients (first 100 each for CEA and CAS in two periods: 2008-2012 and 2018-2022) in a single institution. Assessments used Adenbrooke's Cognitive Examination-Revised (ACE-R), the Mini-Mental State Examination (MMSE), Speech Fluency Test (SFT), and Clock Drawing Test (CDT), conducted before and 30 +/- 2 days after surgery. Results: Patients (mean age 67.2 years, 70%+ carotid stenosis) exhibited different cognitive changes over periods. In 2008-2012, significant declines in MMSE (CEA, p = 0.049) and CDT (CAS, p = 0.015) were observed among asymptomatic patients. On the contrary, in 2018-2022, improvements were observed in ACE-R and MMSE for symptomatic and asymptomatic patients undergoing CEA and CAS. Conclusion: Over a decade, advances in interventional techniques and patient management have reduced risks of cognitive decline in patients with asymptomatic carotid stenosis and also have improved cognitive functions in both symptomatic and asymptomatic individuals.
ER -
VACLAVIK, Daniel, David PAKIZER, Tomas HRBAC, Martin ROUBEC, Vaclav PROCHAZKA, Tomas JONSZTA, Roman HERZIG and David SKOLOUDIK. Changes in Cognitive Functions after Carotid Endarterectomy and Carotid Stenting: A Decade-Apart Comparison. \textit{Biomedicines}. Basel: MDPI, 2024, vol.~12, No~1, p.~1-11. ISSN~2227-9059. Available from: https://dx.doi.org/10.3390/biomedicines12010013.
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