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@article{2427997,
author = {Mužlayová, Patrícia and Danhofer, Pavlína and Španělová, Klára and Kolář, Senad and Horák, Ondřej and Klučka, Jozef and Štourač, Petr and Šenkyřík, Jan and Malá, Miriam and Homola, Lukáš},
article_location = {PRAGUE},
article_number = {3},
doi = {http://dx.doi.org/10.48095/cccsnn2024213},
keywords = {SARS-CoV-2 infection; MIS-C - children; neurological complications; epidemiology},
language = {eng},
issn = {1210-7859},
journal = {Ceska a slovenska neurologie a neurochirurgie},
title = {Prevalence of neurological complications in children hospitalized with SARS-CoV-2 infection or MIS-C in children - single center observational study},
url = {https://www.csnn.eu/casopisy/ceska-slovenska-neurologie/2024-3-8/prevalence-of-neurological-complications-in-children-hospitalized-with-sars-cov-2-infection-or-mis-c-in-children-single-center-observational-study-138162},
volume = {87},
year = {2024}
}
TY - JOUR
ID - 2427997
AU - Mužlayová, Patrícia - Danhofer, Pavlína - Španělová, Klára - Kolář, Senad - Horák, Ondřej - Klučka, Jozef - Štourač, Petr - Šenkyřík, Jan - Malá, Miriam - Homola, Lukáš
PY - 2024
TI - Prevalence of neurological complications in children hospitalized with SARS-CoV-2 infection or MIS-C in children - single center observational study
JF - Ceska a slovenska neurologie a neurochirurgie
VL - 87
IS - 3
SP - 213-219
EP - 213-219
PB - Czech Medical Association J.E. Purkyne
SN - 12107859
KW - SARS-CoV-2 infection
KW - MIS-C - children
KW - neurological complications
KW - epidemiology
UR - https://www.csnn.eu/casopisy/ceska-slovenska-neurologie/2024-3-8/prevalence-of-neurological-complications-in-children-hospitalized-with-sars-cov-2-infection-or-mis-c-in-children-single-center-observational-study-138162
N2 - Introduction: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has caused the enduring global COVID-19 pandemic, which has already begun in late 2019. The virus affects various organs, including the nervous system. This study investigates neurological complications in children with COVID-19 or multisystem inflammatory syndrome in children (MIS-C) in the South Moravia region (Czech republic), where a high COVID-19 rate among children (35.790/100.000) allows for a comprehensive analysis. Methods: Data from the University Hospital Brno (from March 2020 to February 2022) were analyzed to study two groups of hospitalized children diagnosed with COVID-19 or MIS-C: one experiencing neurological complications, and the other without neurological symptoms. The analysis included demographics, admission reasons, infection severity and progression, objective neurological findings, hospitalization details, MIS-C presence and therapies used. Descriptive statistics and statistical testing were employed to assess how individual factors influenced neurological complication rates within these groups. Results: Among 420 hospitalized children with COVID-19 or MIS-C, 26 (6.2%) had neurological complications. Preexisting neurological deficits increased the likelihood of worse outcomes (P = 0.0224). Significant differences in hospitalization length (P = 0.0012), infection severity (P = 0.0052), and outcome (P < 0.0001) occurred between groups. Conclusion: Continuous monitoring and further research on neurological complications in children with COVID-19 or MIS-C are crucial for better understanding of the course of the disease and minimize complications after infection.
ER -
MUŽLAYOVÁ, Patrícia, Pavlína DANHOFER, Klára ŠPANĚLOVÁ, Senad KOLÁŘ, Ondřej HORÁK, Jozef KLUČKA, Petr ŠTOURAČ, Jan ŠENKYŘÍK, Miriam MALÁ and Lukáš HOMOLA. Prevalence of neurological complications in children hospitalized with SARS-CoV-2 infection or MIS-C in children - single center observational study. \textit{Ceska a slovenska neurologie a neurochirurgie}. PRAGUE: Czech Medical Association J.E. Purkyne, 2024, vol.~87, No~3, p.~213-219. ISSN~1210-7859. Available from: https://dx.doi.org/10.48095/cccsnn2024213.
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