VÁŇA, Vladimír, Břetislav LIPOVÝ, L. VACEK, A. PAVELKA, L. JANDA and Jakub HOLOUBEK. Two faces of the antimicrobial peptides and their relevance to burn wound infection. Burns. London: ELSEVIER SCI LTD, 2024, vol. 50, No 7, p. 1938-1940. ISSN 0305-4179. Available from: https://dx.doi.org/10.1016/j.burns.2024.05.014.
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Basic information
Original name Two faces of the antimicrobial peptides and their relevance to burn wound infection
Authors VÁŇA, Vladimír (703 Slovakia, belonging to the institution), Břetislav LIPOVÝ (203 Czech Republic, belonging to the institution), L. VACEK (203 Czech Republic), A. PAVELKA (203 Czech Republic), L. JANDA (203 Czech Republic) and Jakub HOLOUBEK (203 Czech Republic, belonging to the institution).
Edition Burns, London, ELSEVIER SCI LTD, 2024, 0305-4179.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30212 Surgery
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 2.700 in 2022
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1016/j.burns.2024.05.014
UT WoS 001302802100001
Keywords in English Antimicrobial peptides; Immunomodulation; Burn wounds; Cathelicidins
Tags 14110229, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 23/9/2024 14:14.
Abstract
Despite to several modern biomaterials with antimicrobial capacity implemented to wound healing, burn wound infection remains still the most frequent complications within the therapy of these patients. Effectively managing infection not only in the burn wounds is crucial for the successful treatment of patients with burn injuries. Contemporary clinical approaches focused on prompted antibiotic treatment, are facing growing challenges with the increasing resistance exhibited by numerous pathogens. Infections resulting from multi-drug resistant pathogens are recognized to be linked with markedly higher mortality rates compared to those caused by sensitive strains. This underscores the potential of antimicrobial peptides to emerge as future alternative therapeutic modules, offering innovative solutions in the face of limitations encountered by well-established methods.
Links
NU22-05-00475, research and development projectName: Léčba infekcí způsobených multirezistentními kmeny bakterií pomocí nových antibakteriálních přípravků založených na katelicidinových antimikrobiálních peptidech
Investor: Ministry of Health of the CR, Subprogram 1 - standard
PrintDisplayed: 3/10/2024 15:24