Two faces of the antimicrobial peptides and their relevance to
burn wound infection

J 2024

Two faces of the antimicrobial peptides and their relevance to burn wound infection

VÁŇA, Vladimír, Břetislav LIPOVÝ, L. VACEK, A. PAVELKA, L. JANDA et. al.

Basic information

Original name

Two faces of the antimicrobial peptides and their relevance to burn wound infection

Authors

VÁŇA, Vladimír (703 Slovakia, belonging to the institution), Břetislav LIPOVÝ (203 Czech Republic, belonging to the institution), L. VACEK (203 Czech Republic), A. PAVELKA (203 Czech Republic), L. JANDA (203 Czech Republic) and Jakub HOLOUBEK (203 Czech Republic, belonging to the institution)

Edition

Burns, London, ELSEVIER SCI LTD, 2024, 0305-4179

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30212 Surgery

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 2.700 in 2022

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1016/j.burns.2024.05.014

UT WoS

001302802100001

Keywords in English

Antimicrobial peptides; Immunomodulation; Burn wounds; Cathelicidins

Abstract

V originále

Despite to several modern biomaterials with antimicrobial capacity implemented to wound healing, burn wound infection remains still the most frequent complications within the therapy of these patients. Effectively managing infection not only in the burn wounds is crucial for the successful treatment of patients with burn injuries. Contemporary clinical approaches focused on prompted antibiotic treatment, are facing growing challenges with the increasing resistance exhibited by numerous pathogens. Infections resulting from multi-drug resistant pathogens are recognized to be linked with markedly higher mortality rates compared to those caused by sensitive strains. This underscores the potential of antimicrobial peptides to emerge as future alternative therapeutic modules, offering innovative solutions in the face of limitations encountered by well-established methods.

Links

NU22-05-00475, research and development project

Name: Léčba infekcí způsobených multirezistentními kmeny bakterií pomocí nových antibakteriálních přípravků založených na katelicidinových antimikrobiálních peptidech

Investor: Ministry of Health of the CR, Subprogram 1 - standard

Citovat

VÁŇA, Vladimír, Břetislav LIPOVÝ, L. VACEK, A. PAVELKA, L. JANDA and Jakub HOLOUBEK. Two faces of the antimicrobial peptides and their relevance to burn wound infection. Burns. London: ELSEVIER SCI LTD, 2024, vol. 50, No 7, p. 1938-1940. ISSN 0305-4179. Available from: https://dx.doi.org/10.1016/j.burns.2024.05.014.

@article{2436138,
   author = {Váňa, Vladimír and Lipový, Břetislav and Vacek, L. and Pavelka, A. and Janda, L. and Holoubek, Jakub},
   article_location = {London},
   article_number = {7},
   doi = {http://dx.doi.org/10.1016/j.burns.2024.05.014},
   keywords = {Antimicrobial peptides; Immunomodulation; Burn wounds; Cathelicidins},
   language = {eng},
   issn = {0305-4179},
   journal = {Burns},
   title = {Two faces of the antimicrobial peptides and their relevance to burn wound infection},
   url = {https://www.sciencedirect.com/science/article/pii/S0305417924001554?via%3Dihub},
   volume = {50},
   year = {2024}
}

TY  - JOUR
ID  - 2436138
AU  - Váňa, Vladimír - Lipový, Břetislav - Vacek, L. - Pavelka, A. - Janda, L. - Holoubek, Jakub
PY  - 2024
TI  - Two faces of the antimicrobial peptides and their relevance to burn wound infection
JF  - Burns
VL  - 50
IS  - 7
SP  - 1938-1940
EP  - 1938-1940
PB  - ELSEVIER SCI LTD
SN  - 03054179
KW  - Antimicrobial peptides
KW  - Immunomodulation
KW  - Burn wounds
KW  - Cathelicidins
UR  - https://www.sciencedirect.com/science/article/pii/S0305417924001554?via%3Dihub
N2  - Despite to several modern biomaterials with antimicrobial capacity implemented to wound healing, burn wound infection remains still the most frequent complications within the therapy of these patients. Effectively managing infection not only in the burn wounds is crucial for the successful treatment of patients with burn injuries. Contemporary clinical approaches focused on prompted antibiotic treatment, are facing growing challenges with the increasing resistance exhibited by numerous pathogens. Infections resulting from multi-drug resistant pathogens are recognized to be linked with markedly higher mortality rates compared to those caused by sensitive strains. This underscores the potential of antimicrobial peptides to emerge as future alternative therapeutic modules, offering innovative solutions in the face of limitations encountered by well-established methods.
ER  -

VÁŇA, Vladimír, Břetislav LIPOVÝ, L. VACEK, A. PAVELKA, L. JANDA and Jakub HOLOUBEK. Two faces of the antimicrobial peptides and their relevance to burn wound infection. \textit{Burns}. London: ELSEVIER SCI LTD, 2024, vol.~50, No~7, p.~1938-1940. ISSN~0305-4179. Available from: https://dx.doi.org/10.1016/j.burns.2024.05.014.

Detailed Information on Publication Record