A normal electrocardiogram indicates a better prognosis in
patients with moderate to very severe chronic obstructive
pulmonary disease

J 2025

A normal electrocardiogram indicates a better prognosis in patients with moderate to very severe chronic obstructive pulmonary disease

KULIROVA, Martina; Miroslav SOLAR; Michal KOPECKY; Barbora NOVOTNA; Marek PLUTINSKÝ et. al.

Základní údaje

Originální název

A normal electrocardiogram indicates a better prognosis in patients with moderate to very severe chronic obstructive pulmonary disease

Autoři

KULIROVA, Martina (203 Česká republika); Miroslav SOLAR (203 Česká republika); Michal KOPECKY (203 Česká republika); Barbora NOVOTNA (203 Česká republika); Marek PLUTINSKÝ (703 Slovensko); Kristián BRAT (703 Slovensko); Libor FILA (203 Česká republika); Petr VANIK (203 Česká republika); Pavlina MUSILOVA (203 Česká republika); Tomas DVORAK (203 Česká republika); Petr SAFRANEK (203 Česká republika); Michal SVOBODA (203 Česká republika, domácí) a Vladimir KOBLIZEK (203 Česká republika)

Vydání

Nature Scientific Reports, BERLIN, NATURE PORTFOLIO, 2025, 2045-2322

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30203 Respiratory systems

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.800 v roce 2023

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1038/s41598-025-89013-0

UT WoS

001415489100015

EID Scopus

2-s2.0-85218243401

Klíčová slova anglicky

Chronic obstructive pulmonary disease; Electrocardiography; Mortality; Prognosis

Štítky

14119612, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 27. 3. 2025 08:33, Mgr. Tereza Miškechová

Anotace

V originále

The role of electrocardiography (ECG) in predicting mortality in patients with chronic obstructive pulmonary disease (COPD) has not been sufficiently established. Research question: Is a normal ECG associated with a better prognosis than an abnormal ECG in patients with COPD? ECG parameters were assessed in patients enrolled in the Czech Multicenter Research Database of COPD. We assessed ECGs from baseline (August 2013) until December 31, 2019, or until death. The primary endpoint was 5-year overall survival depending on the ECG findings. A total of 300 subjects were enrolled in the study and 143 died during follow-up. This multicenter noninterventional observational prospective study revealed a significant difference in 5-year overall survival between COPD patients with normal ECGs and those with prognostically significant or other ECG abnormalities (76.8%, 38.2%, and 63.4%, respectively; P < 0.001). Patients with prognostically significant ECG abnormalities had a 2.537-fold greater mortality risk at 5 years than those with normal ECGs. In the COPD setting, patients with normal ECGs had a better prognosis than those with prognostically significant abnormalities suggesting that ECG may be a valuable tool for predicting mortality risk in these patients.

Návaznosti

90249, velká výzkumná infrastruktura

Název: CZECRIN IV

Citovat

KULIROVA, Martina; Miroslav SOLAR; Michal KOPECKY; Barbora NOVOTNA; Marek PLUTINSKÝ; Kristián BRAT; Libor FILA; Petr VANIK; Pavlina MUSILOVA; Tomas DVORAK; Petr SAFRANEK; Michal SVOBODA a Vladimir KOBLIZEK. A normal electrocardiogram indicates a better prognosis in patients with moderate to very severe chronic obstructive pulmonary disease. Nature Scientific Reports. BERLIN: NATURE PORTFOLIO, 2025, roč. 15, č. 1, s. 1-12. ISSN 2045-2322. Dostupné z: https://dx.doi.org/10.1038/s41598-025-89013-0.

@article{2481321,
   author = {Kulirova, Martina and Solar, Miroslav and Kopecky, Michal and Novotna, Barbora and Plutinský, Marek and Brat, Kristián and Fila, Libor and Vanik, Petr and Musilova, Pavlina and Dvorak, Tomas and Safranek, Petr and Svoboda, Michal and Koblizek, Vladimir},
   article_location = {BERLIN},
   article_number = {1},
   doi = {http://dx.doi.org/10.1038/s41598-025-89013-0},
   keywords = {Chronic obstructive pulmonary disease; Electrocardiography; Mortality; Prognosis},
   language = {eng},
   issn = {2045-2322},
   journal = {Nature Scientific Reports},
   title = {A normal electrocardiogram indicates a better prognosis in patients with moderate to very severe chronic obstructive pulmonary disease},
   url = {https://www.nature.com/articles/s41598-025-89013-0},
   volume = {15},
   year = {2025}
}

TY  - JOUR
ID  - 2481321
AU  - Kulirova, Martina - Solar, Miroslav - Kopecky, Michal - Novotna, Barbora - Plutinský, Marek - Brat, Kristián - Fila, Libor - Vanik, Petr - Musilova, Pavlina - Dvorak, Tomas - Safranek, Petr - Svoboda, Michal - Koblizek, Vladimir
PY  - 2025
TI  - A normal electrocardiogram indicates a better prognosis in patients with moderate to very severe chronic obstructive pulmonary disease
JF  - Nature Scientific Reports
VL  - 15
IS  - 1
SP  - 1-12
EP  - 1-12
PB  - NATURE PORTFOLIO
SN  - 20452322
KW  - Chronic obstructive pulmonary disease
KW  - Electrocardiography
KW  - Mortality
KW  - Prognosis
UR  - https://www.nature.com/articles/s41598-025-89013-0
N2  - The role of electrocardiography (ECG) in predicting mortality in patients with chronic obstructive pulmonary disease (COPD) has not been sufficiently established. Research question: Is a normal ECG associated with a better prognosis than an abnormal ECG in patients with COPD? ECG parameters were assessed in patients enrolled in the Czech Multicenter Research Database of COPD. We assessed ECGs from baseline (August 2013) until December 31, 2019, or until death. The primary endpoint was 5-year overall survival depending on the ECG findings. A total of 300 subjects were enrolled in the study and 143 died during follow-up. This multicenter noninterventional observational prospective study revealed a significant difference in 5-year overall survival between COPD patients with normal ECGs and those with prognostically significant or other ECG abnormalities (76.8%, 38.2%, and 63.4%, respectively; P < 0.001). Patients with prognostically significant ECG abnormalities had a 2.537-fold greater mortality risk at 5 years than those with normal ECGs. In the COPD setting, patients with normal ECGs had a better prognosis than those with prognostically significant abnormalities suggesting that ECG may be a valuable tool for predicting mortality risk in these patients.
ER  -

KULIROVA, Martina; Miroslav SOLAR; Michal KOPECKY; Barbora NOVOTNA; Marek PLUTINSKÝ; Kristián BRAT; Libor FILA; Petr VANIK; Pavlina MUSILOVA; Tomas DVORAK; Petr SAFRANEK; Michal SVOBODA a Vladimir KOBLIZEK. A normal electrocardiogram indicates a better prognosis in patients with moderate to very severe chronic obstructive pulmonary disease. \textit{Nature Scientific Reports}. BERLIN: NATURE PORTFOLIO, 2025, roč.~15, č.~1, s.~1-12. ISSN~2045-2322. Dostupné z: https://dx.doi.org/10.1038/s41598-025-89013-0.

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