Sacrococcygeal teratoma - prognosis based on prenatal
ultrasound diagnosis, single-center experience and literature
review

J 2025

Sacrococcygeal teratoma - prognosis based on prenatal ultrasound diagnosis, single-center experience and literature review

JOUZOVÁ, Anna; Martin JOUZA; Jakub TUREK; Romana GERYCHOVÁ; Marta JEŽOVÁ et. al.

Základní údaje

Originální název

Sacrococcygeal teratoma - prognosis based on prenatal ultrasound diagnosis, single-center experience and literature review

Autoři

JOUZOVÁ, Anna (203 Česká republika, domácí); Martin JOUZA (203 Česká republika, domácí); Jakub TUREK (703 Slovensko, domácí); Romana GERYCHOVÁ (203 Česká republika, domácí); Marta JEŽOVÁ (203 Česká republika); Petr JANKŮ (203 Česká republika, domácí) a Lukáš HRUBAN (203 Česká republika, domácí)

Vydání

BMC Pregnancy and Childbirth, London, BMC, 2025, 1471-2393

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30214 Obstetrics and gynaecology

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 2.700 v roce 2024

Organizační jednotka

Lékařská fakulta

DOI

https://doi.org/10.1186/s12884-025-07494-3

UT WoS

001473843100006

EID Scopus

2-s2.0-105003273341

Klíčová slova anglicky

Sacrococcygeal teratoma; Congenital tumor; Prenatal diagnosis; Ultrasound; Prognosis; Prenatal counseling

Štítky

14110240, 14110313, 14110317, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 3. 6. 2025 12:49, Mgr. Tereza Miškechová

Anotace

V originále

IntroductionSacrococcygeal teratoma (SCT) is the most common congenital tumor. The incidence of malignant types is rare but increases with late detection or in case of relapse. Prenatal diagnosis is based on ultrasound examination and magnetic resonance imaging (MRI). Since this is a rare congenital anomaly, we should report all cases to improve prenatal diagnosis and postnatal management.Material and methodsRetrospective analysis of sixteen cases of sacrococcygeal teratoma delivered and treated at the University Hospital Brno between 2005 and 2020. The following criteria were evaluated: gestational week of the primary diagnosis, exact description of ultrasound findings, pregnancy management, delivery mode, correlation of prenatal ultrasound with postnatal findings in the newborn, as well as the occurrence of early and late complications in newborns and children.ResultsOut of sixteen cases, seven cases (43.8%) were indicated for pregnancy termination based on ultrasound findings, the parent's decision, and an estimation of an adverse pregnancy outcome. In nine cases (56.2%), the pregnancy continued and was ended by delivery. In one case, there was an early postnatal death of a newborn after birth in the 25th week of gestation. In eight cases, live fetuses were born in which the tumor was surgically removed between day 1 and 14 months after birth. There was a strong correlation between the tumor description made by prenatal ultrasound diagnosis and related severe complications in newborns. The incidence of severe early and late complications in ongoing pregnancies was very low-only one case of infection in the surgical wound requiring reoperation (12.5%) was described. In two patients (25%), a transient stoma establishment was necessary for secondary ileus. One case of recurrence of the disease at two years of age occurred, requiring the administration of chemotherapy (12.5%), and one patient has mild persistent urinary incontinence.ConclusionSacrococcygeal teratoma is one of the rarest congenital malformations. A detailed prenatal ultrasound examination is essential to estimate the pregnancy prognosis. The most predictive ultrasound predictor of favorable early and late postnatal outcomes and long-term child development is the presence of cystic sacrococcygeal formation, the most common tumor type, and the absence of signs of cardiac failure due to fetal anemia. In these cases, with early surgical treatment provided, the incidence of severe complications and long-term consequences in children is very low, and parents should be informed during prenatal counseling. It is necessary to register all the SCT cases due to the rarity of this congenital anomaly for further statistical analysis of the importance of ultrasound markers.

Citovat

JOUZOVÁ, Anna; Martin JOUZA; Jakub TUREK; Romana GERYCHOVÁ; Marta JEŽOVÁ; Petr JANKŮ a Lukáš HRUBAN. Sacrococcygeal teratoma - prognosis based on prenatal ultrasound diagnosis, single-center experience and literature review. BMC Pregnancy and Childbirth. London: BMC, 2025, roč. 25, č. 1, s. 1-9. ISSN 1471-2393. Dostupné z: https://doi.org/10.1186/s12884-025-07494-3.

@article{2501024,
   author = {Jouzová, Anna and Jouza, Martin and Turek, Jakub and Gerychová, Romana and Ježová, Marta and Janků, Petr and Hruban, Lukáš},
   article_location = {London},
   article_number = {1},
   doi = {https://doi.org/10.1186/s12884-025-07494-3},
   keywords = {Sacrococcygeal teratoma; Congenital tumor; Prenatal diagnosis; Ultrasound; Prognosis; Prenatal counseling},
   language = {eng},
   issn = {1471-2393},
   journal = {BMC Pregnancy and Childbirth},
   title = {Sacrococcygeal teratoma - prognosis based on prenatal ultrasound diagnosis, single-center experience and literature review},
   url = {https://bmcpregnancychildbirth.biomedcentral.com/articles/10.1186/s12884-025-07494-3},
   volume = {25},
   year = {2025}
}

TY  - JOUR
ID  - 2501024
AU  - Jouzová, Anna - Jouza, Martin - Turek, Jakub - Gerychová, Romana - Ježová, Marta - Janků, Petr - Hruban, Lukáš
PY  - 2025
TI  - Sacrococcygeal teratoma - prognosis based on prenatal ultrasound diagnosis, single-center experience and literature review
JF  - BMC Pregnancy and Childbirth
VL  - 25
IS  - 1
SP  - 1-9
EP  - 1-9
PB  - BMC
SN  - 14712393
KW  - Sacrococcygeal teratoma
KW  - Congenital tumor
KW  - Prenatal diagnosis
KW  - Ultrasound
KW  - Prognosis
KW  - Prenatal counseling
UR  - https://bmcpregnancychildbirth.biomedcentral.com/articles/10.1186/s12884-025-07494-3
N2  - IntroductionSacrococcygeal teratoma (SCT) is the most common congenital tumor. The incidence of malignant types is rare but increases with late detection or in case of relapse. Prenatal diagnosis is based on ultrasound examination and magnetic resonance imaging (MRI). Since this is a rare congenital anomaly, we should report all cases to improve prenatal diagnosis and postnatal management.Material and methodsRetrospective analysis of sixteen cases of sacrococcygeal teratoma delivered and treated at the University Hospital Brno between 2005 and 2020. The following criteria were evaluated: gestational week of the primary diagnosis, exact description of ultrasound findings, pregnancy management, delivery mode, correlation of prenatal ultrasound with postnatal findings in the newborn, as well as the occurrence of early and late complications in newborns and children.ResultsOut of sixteen cases, seven cases (43.8%) were indicated for pregnancy termination based on ultrasound findings, the parent's decision, and an estimation of an adverse pregnancy outcome. In nine cases (56.2%), the pregnancy continued and was ended by delivery. In one case, there was an early postnatal death of a newborn after birth in the 25th week of gestation. In eight cases, live fetuses were born in which the tumor was surgically removed between day 1 and 14 months after birth. There was a strong correlation between the tumor description made by prenatal ultrasound diagnosis and related severe complications in newborns. The incidence of severe early and late complications in ongoing pregnancies was very low-only one case of infection in the surgical wound requiring reoperation (12.5%) was described. In two patients (25%), a transient stoma establishment was necessary for secondary ileus. One case of recurrence of the disease at two years of age occurred, requiring the administration of chemotherapy (12.5%), and one patient has mild persistent urinary incontinence.ConclusionSacrococcygeal teratoma is one of the rarest congenital malformations. A detailed prenatal ultrasound examination is essential to estimate the pregnancy prognosis. The most predictive ultrasound predictor of favorable early and late postnatal outcomes and long-term child development is the presence of cystic sacrococcygeal formation, the most common tumor type, and the absence of signs of cardiac failure due to fetal anemia. In these cases, with early surgical treatment provided, the incidence of severe complications and long-term consequences in children is very low, and parents should be informed during prenatal counseling. It is necessary to register all the SCT cases due to the rarity of this congenital anomaly for further statistical analysis of the importance of ultrasound markers.
ER  -

JOUZOVÁ, Anna; Martin JOUZA; Jakub TUREK; Romana GERYCHOVÁ; Marta JEŽOVÁ; Petr JANKŮ a Lukáš HRUBAN. Sacrococcygeal teratoma - prognosis based on prenatal ultrasound diagnosis, single-center experience and literature review. \textit{BMC Pregnancy and Childbirth}. London: BMC, 2025, roč.~25, č.~1, s.~1-9. ISSN~1471-2393. Dostupné z: https://doi.org/10.1186/s12884-025-07494-3.

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