Retinal Vessel Oxygen Saturation in Patients with Unilateral
Edema of the Optic Nerve Head: A Pilot Study

J 2025

Retinal Vessel Oxygen Saturation in Patients with Unilateral Edema of the Optic Nerve Head: A Pilot Study

BŘEZÍK, Michal; Veronika MATUŠKOVÁ; Daniela VYSLOUŽILOVÁ; M. ŠÍN; Veronika CHOVANCOVÁ et. al.

Základní údaje

Originální název

Retinal Vessel Oxygen Saturation in Patients with Unilateral Edema of the Optic Nerve Head: A Pilot Study

Autoři

BŘEZÍK, Michal; Veronika MATUŠKOVÁ; Daniela VYSLOUŽILOVÁ; M. ŠÍN; Veronika CHOVANCOVÁ; Kristína SIČOVÁ; N. JANKANIČOVÁ a Oldřich CHRAPEK

Vydání

Eye and Brain, ALBANY, DOVE MEDICAL PRESS LTD, 2025, 1179-2744

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30207 Ophthalmology

Stát vydavatele

Nový Zéland

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.100 v roce 2023

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.2147/EB.S524274

UT WoS

999

EID Scopus

999

Klíčová slova anglicky

retina; oximetry; papilledema; microcirculation

Štítky

14110219

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 10. 7. 2025 12:19, Mgr. Tereza Miškechová

Anotace

V originále

Purpose: Evaluate whether optic disc edema results in changes in retinal microcirculation. Patients and Methods: The study group consisted of 11 patients with unilateral optic disc edema (papilledema). The control group consisted of the healthy eyes of the same 11 patients. Patients underwent non-invasive photo-spectrometric retinal oximetry using Oxymap T1 retinal oximeter (Oxymap, Reykjavik, Iceland). In the eyes of these 11 patients, we examined the diameter of the retinal arteries and veins, arterial and venous blood oxygen saturation, and the difference in oxygen saturation between arterioles and venules (A-V difference). Results: In the papilledema group, the decrease in the retinal arterial diameter was statistically significant (p=0.001). The median diameter of the retinal artery was 11.70 px (IQR 1.47) or after conversion 109.00 μm (IQR 14.00) in the papilledema group and 13.75 px (IQR 1.61) or 128.00 μm (IQR 15.00) in the control group. The increase in the diameter of the retinal veins in the papilledema group was statistically significant (p=0.012), where the median diameter in the papilledema group was 20.88 px (IQR 3.72) or 194.00 μm (IQR 35.00), and in the control group was 18.18 px (IQR 3.60) or 169 μm (IQR 33.00). There was a statistically significant decrease (p< 0.001) in the venous saturation in the papilledema group with a median value of 53.16% (IQR 17.38) and 60.02% (IQR 11.98) in the control group. The median of the A-V difference was 51.92 (IQR 15.96) in the papilledema group, resp. 38.49 (IQR 9.75) in the control group and a significant increase in the papilledema group (p< 0.001) was reported. Conclusion: Automatic retinal oximetry demonstrated changes in the retinal microcirculation in patients with optic disc edema.

Citovat

BŘEZÍK, Michal; Veronika MATUŠKOVÁ; Daniela VYSLOUŽILOVÁ; M. ŠÍN; Veronika CHOVANCOVÁ; Kristína SIČOVÁ; N. JANKANIČOVÁ a Oldřich CHRAPEK. Retinal Vessel Oxygen Saturation in Patients with Unilateral Edema of the Optic Nerve Head: A Pilot Study. Eye and Brain. ALBANY: DOVE MEDICAL PRESS LTD, 2025, roč. 17, s. 81-94. ISSN 1179-2744. Dostupné z: https://dx.doi.org/10.2147/EB.S524274.

@article{2508003,
   author = {Březík, Michal and Matušková, Veronika and Vysloužilová, Daniela and Šín, M. and Chovancová, Veronika and Sičová, Kristína and Jankaničová, N. and Chrapek, Oldřich},
   article_location = {ALBANY},
   doi = {http://dx.doi.org/10.2147/EB.S524274},
   keywords = {retina; oximetry; papilledema; microcirculation},
   language = {eng},
   issn = {1179-2744},
   journal = {Eye and Brain},
   title = {Retinal Vessel Oxygen Saturation in Patients with Unilateral Edema of the Optic Nerve Head: A Pilot Study},
   url = {https://www.dovepress.com/retinal-vessel-oxygen-saturation-in-patients-with-unilateral-edema-of--peer-reviewed-fulltext-article-EB},
   volume = {17},
   year = {2025}
}

TY  - JOUR
ID  - 2508003
AU  - Březík, Michal - Matušková, Veronika - Vysloužilová, Daniela - Šín, M. - Chovancová, Veronika - Sičová, Kristína - Jankaničová, N. - Chrapek, Oldřich
PY  - 2025
TI  - Retinal Vessel Oxygen Saturation in Patients with Unilateral Edema of the Optic Nerve Head: A Pilot Study
JF  - Eye and Brain
VL  - 17
SP  - 81-94
EP  - 81-94
PB  - DOVE MEDICAL PRESS LTD
SN  - 11792744
KW  - retina
KW  - oximetry
KW  - papilledema
KW  - microcirculation
UR  - https://www.dovepress.com/retinal-vessel-oxygen-saturation-in-patients-with-unilateral-edema-of--peer-reviewed-fulltext-article-EB
N2  - Purpose: Evaluate whether optic disc edema results in changes in retinal microcirculation. Patients and Methods: The study group consisted of 11 patients with unilateral optic disc edema (papilledema). The control group consisted of the healthy eyes of the same 11 patients. Patients underwent non-invasive photo-spectrometric retinal oximetry using Oxymap T1 retinal oximeter (Oxymap, Reykjavik, Iceland). In the eyes of these 11 patients, we examined the diameter of the retinal arteries and veins, arterial and venous blood oxygen saturation, and the difference in oxygen saturation between arterioles and venules (A-V difference). Results: In the papilledema group, the decrease in the retinal arterial diameter was statistically significant (p=0.001). The median diameter of the retinal artery was 11.70 px (IQR 1.47) or after conversion 109.00 μm (IQR 14.00) in the papilledema group and 13.75 px (IQR 1.61) or 128.00 μm (IQR 15.00) in the control group. The increase in the diameter of the retinal veins in the papilledema group was statistically significant (p=0.012), where the median diameter in the papilledema group was 20.88 px (IQR 3.72) or 194.00 μm (IQR 35.00), and in the control group was 18.18 px (IQR 3.60) or 169 μm (IQR 33.00). There was a statistically significant decrease (p< 0.001) in the venous saturation in the papilledema group with a median value of 53.16% (IQR 17.38) and 60.02% (IQR 11.98) in the control group. The median of the A-V difference was 51.92 (IQR 15.96) in the papilledema group, resp. 38.49 (IQR 9.75) in the control group and a significant increase in the papilledema group (p< 0.001) was reported. Conclusion: Automatic retinal oximetry demonstrated changes in the retinal microcirculation in patients with optic disc edema.
ER  -

BŘEZÍK, Michal; Veronika MATUŠKOVÁ; Daniela VYSLOUŽILOVÁ; M. ŠÍN; Veronika CHOVANCOVÁ; Kristína SIČOVÁ; N. JANKANIČOVÁ a Oldřich CHRAPEK. Retinal Vessel Oxygen Saturation in Patients with Unilateral Edema of the Optic Nerve Head: A Pilot Study. \textit{Eye and Brain}. ALBANY: DOVE MEDICAL PRESS LTD, 2025, roč.~17, s.~81-94. ISSN~1179-2744. Dostupné z: https://dx.doi.org/10.2147/EB.S524274.

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