| FULNEČKOVÁ, Jana a Jiří FAJKUS. Inhibition of plant telomerase by telomere-binding proteins from nuclei of telomerase-negatative tissues. Online. FEBS letters : for the rapid publication of short reports in biochemistry, biophysics and molecular biology. Amsterdam: North-Holland, 2000, roč. 467, 2-3, s. 305-310. ISSN 0014-5793. [citováno 2024-04-24] |
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@article{315291,
author = {Fulnečková, Jana and Fajkus, Jiří},
article_location = {Amsterdam},
article_number = {2-3},
keywords = {Plant telomerase regulation; Telomere binding protein; Telomerase inhibition},
language = {eng},
issn = {0014-5793},
journal = {FEBS letters : for the rapid publication of short reports in biochemistry, biophysics and molecular biology},
title = {Inhibition of plant telomerase by telomere-binding proteins from nuclei of telomerase-negatative tissues},
volume = {467},
year = {2000}
}
TY - JOUR
ID - 315291
AU - Fulnečková, Jana - Fajkus, Jiří
PY - 2000
TI - Inhibition of plant telomerase by telomere-binding proteins from nuclei of telomerase-negatative tissues
JF - FEBS letters : for the rapid publication of short reports in biochemistry, biophysics and molecular biology
VL - 467
IS - 2-3
SP - 305
EP - 305
PB - North-Holland
SN - 00145793
KW - Plant telomerase regulation
KW - Telomere binding protein
KW - Telomerase inhibition
N2 - The activity of telomerase in plant cells is precisely regulated in response to changes in cell division rate. To explore this regulatory mechanism, the effect on telomerase activity of protein extracts from nuclei of telomerase-negative tissues was examined. An inhibition of telomerase activity was found which was species-non-specific. This inhibition was due to proteins which form salt-stable, sequence- specific complexes with the G-rich telomeric strand and reduce its accessibility, as shown by gel retardation and by terminal transferase (TdT) extension of G-rich telomeric and non-telomeric (substrate) primers. A 40 kDa polypeptide was detected by SDS-PAGE after cross- linking the complex formed by extracts from tobacco leaf nuclei. Such proteins may be involved in regulation of telomerase activity in plants.
ER -
FULNEČKOVÁ, Jana a Jiří FAJKUS. Inhibition of plant telomerase by telomere-binding proteins from nuclei of telomerase-negatative tissues. Online. \textit{FEBS letters : for the rapid publication of short reports in biochemistry, biophysics and molecular biology}. Amsterdam: North-Holland, 2000, roč.~467, 2-3, s.~305-310. ISSN~0014-5793. [citováno 2024-04-24]
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