ISHIGURO, Junpei, Shin-ichiro SHIMADA, Miroslav GABRIEL and Marie KOPECKÁ. Characterization of a fission yeast mutant which displays defects in cell wall integrity and cytokinesis. In Tenth International Symposium on Yeasts The rising power of yeasts in science and industry. Delft University Press 2000. Delft University Press, The Netherlands: Johannes P. van Dijken and W.Alexander Scheffers (editors), Kluyver Lab. Biotechnol.Delft Universityx of Technology, 2000, p. 173-173, 2 pp. ISBN 90-407-2067-3.
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Basic information
Original name Characterization of a fission yeast mutant which displays defects in cell wall integrity and cytokinesis
Authors ISHIGURO, Junpei (392 Japan, guarantor), Shin-ichiro SHIMADA (392 Japan), Miroslav GABRIEL (203 Czech Republic, belonging to the institution) and Marie KOPECKÁ (203 Czech Republic, belonging to the institution).
Edition Delft University Press 2000. Delft University Press, The Netherlands, Tenth International Symposium on Yeasts The rising power of yeasts in science and industry, p. 173-173, 2 pp. 2000.
Publisher Johannes P. van Dijken and W.Alexander Scheffers (editors), Kluyver Lab. Biotechnol.Delft Universityx of Technology
Other information
Original language English
Type of outcome Proceedings paper
Field of Study 10600 1.6 Biological sciences
Country of publisher Netherlands
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14110/00:00003325
Organization unit Faculty of Medicine
ISBN 90-407-2067-3
UT WoS 000171979300007
Keywords in English yeasts; fission; mutant; cell wall; cytokinesis
Tags Cell wall, cytokinesis, fission, MUTANT, yeasts
Changed by Changed by: prof. MUDr. Marie Kopecká, CSc., učo 2342. Changed: 10/3/2011 10:01.
Abstract
Cps mutants of S.pombe were isolated as supersensitive to spindle poison isopropyl 3-N-chlorophenyl carbamate.Cps6-153 mutant reveals wall weakness and defects in cytokinesis and cell morphology. The aim of this work was to describe cytoskeleton and wall ultrastructure.Actin cytoskeleton reflected accumulation of wall material at poles and septum region.Cytoplasmic microtubules revealed abnormal alignment. The wall was less compact and more spongy with predominance of microfibrils.It is suggested that cps6 may function in regulation of cell wall integrity and cytokinesis in Ras-related signalling patway via interaction with the cytoskeletal organizaction.
Links
GA204/00/0394, research and development projectName: Buněčná stěna kvasinek jako extracelulární matrix: cytoskelet a stěnové funkce
Investor: Czech Science Foundation, The yeast cell wall as an extracellular matrix: cytoskeleton and cell wall functions
GA310/00/0391, research and development projectName: Cytoskelet u lidských patogenních kvasinkových mikroorganismů.
Investor: Czech Science Foundation, Cytoskeleton in human pathogenic yeast microorganisms
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