J 2000

Functional polymorphism in the gelationase B gene and asthma

IZAKOVICOVA HOLLA, Lydie, Anna VAŠKŮ, Andrea STEJSKALOVÁ and Vladimír ZNOJIL

Basic information

Original name

Functional polymorphism in the gelationase B gene and asthma

Authors

IZAKOVICOVA HOLLA, Lydie (203 Czech Republic, guarantor), Anna VAŠKŮ (203 Czech Republic), Andrea STEJSKALOVÁ (203 Czech Republic) and Vladimír ZNOJIL (203 Czech Republic)

Edition

Allergy, Denmark, Munksgaard International Publishers, 2000, 0105-4538

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30102 Immunology

Country of publisher

Denmark

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 2.385

RIV identification code

RIV/00216224:14110/00:00002359

Organization unit

Faculty of Medicine

UT WoS

000088975100022

Keywords in English

gene; polymorphism; MMP-9; matrix metalloproteinase; asthma

Tags

Změněno: 17/6/2009 13:32, prof. MUDr. Lydie Izakovičová Hollá, Ph.D.

Abstract

V originále

Gelatinase B, a matrix metalloproteinase that has proteolytic activity against connective tissue proteins, has been suggested to be important in the chronic structural airway changes in asthma. This study tested the hypothesis that the functional polymorphism in the regulatory region of gelatinase B gene is associated with asthma bronchiale.

Links

MSM 141100002, plan (intention)
Name: Molekulární patofyziologie multigenních chorob
Investor: Ministry of Education, Youth and Sports of the CR, Molecular pathophysiology of multigene diseases
VS96097, research and development project
Name: Molekulární patofyziologie vybraných "civilizačních", multigenně podmíněných chorob
Investor: Ministry of Education, Youth and Sports of the CR, Molecular pathophysiology of selected multigenic related to civilization diseases