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@inproceedings{344896,
author = {Svíženská, Ivana and Dubový, Petr},
address = {Praha},
booktitle = {Sborník lékařský},
keywords = {extracellular matrix; peripheral nerve; entubulation; regeneration},
language = {eng},
location = {Praha},
pages = {31-31},
publisher = {Karlova univerzita},
title = {Immunohistochemical analysis of some ECM components in the nerve outgrowth regenerating through the knitted tubes.},
year = {2000}
}
TY - JOUR
ID - 344896
AU - Svíženská, Ivana - Dubový, Petr
PY - 2000
TI - Immunohistochemical analysis of some ECM components in the nerve outgrowth regenerating through the knitted tubes.
PB - Karlova univerzita
CY - Praha
KW - extracellular matrix
KW - peripheral nerve
KW - entubulation
KW - regeneration
N2 - The synthesis of the extracellular matrix (ECM) is an inevitable condition for the peripheral nerve regeneration. We investigated several components of the ECM (fibronectin, collagen IV, thrombospondin, chondroitin sulfate, and vitronectin) by the indirect immunohistochemical method in cryostat cross sections through nerve regenerates obtained from 6 adult female rats. The regenerate rejoined the proximal and distal stumps of the transected sciatic nerve that had been inserted into the guide prepared from the knitted vascular prosthesis. After 6 weeks from the transection, the regenerate consisted of a band of axons arranged in fascicles running along the longitudinal axis of the prosthesis. Our immunohistochemical results suggest that the ECM produced in the knitted vascular tube provides a milieu suitable for nerve regeneration.
ER -
SVÍŽENSKÁ, Ivana and Petr DUBOVÝ. Immunohistochemical analysis of some ECM components in the nerve outgrowth regenerating through the knitted tubes. In \textit{Sborník lékařský}. Praha: Karlova univerzita, 2000, p.~31.
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