DRÁBKOVÁ, Marie, Marie VOJTÍŠKOVÁ, Anna VAŠKŮ, Tomáš BURNOG, Petr JANKŮ and Kateřina KAŇKOVÁ. Factor V Leiden in Patients with recurrent Fetal Loss. In Book of Abstracts of XVI. FIGO World Congress. Washington D.C.: Congress of Gynecology and Obstetrics, 2000, p. 142.
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Basic information
Original name Factor V Leiden in Patients with recurrent Fetal Loss
Authors DRÁBKOVÁ, Marie (203 Czech Republic, guarantor), Marie VOJTÍŠKOVÁ (203 Czech Republic), Anna VAŠKŮ (203 Czech Republic), Tomáš BURNOG (203 Czech Republic), Petr JANKŮ (203 Czech Republic) and Kateřina KAŇKOVÁ (203 Czech Republic).
Edition Washington D.C. Book of Abstracts of XVI. FIGO World Congress, p. 142-142, 2000.
Publisher Congress of Gynecology and Obstetrics
Other information
Original language English
Type of outcome Proceedings paper
Field of Study Genetics and molecular biology
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14110/00:00002625
Organization unit Faculty of Medicine
Keywords in English Factor V Leiden; fetal loss
Tags Factor V Leiden, fetal loss
Changed by Changed by: prof. MUDr. Anna Vašků, CSc., učo 122. Changed: 24/4/2003 10:17.
Abstract
S u m m a r y: The factor V Leiden mutation is the most common genetic predisposition to thrombosis. Our purpose was to determine the association of Factor V Leiden mutation (FVL) frequency and recurrent fetal loss.We examined the prevalence of the point mutation in the factor V gene (R 506 Q or Leiden) in 138 unselected women with a history of one or more spontaneous abortion or stillbirth of unexplained etiology. In our referral population women, a statistically significant association of the Leiden mutation with recurrent fetal losses was found. The risk for recurrence of fetal loss tended to be greater in homozygous carriers.
Links
MSM 141100002, plan (intention)Name: Molekulární patofyziologie multigenních chorob
Investor: Ministry of Education, Youth and Sports of the CR, Molecular pathophysiology of multigene diseases
VS96097, research and development projectName: Molekulární patofyziologie vybraných "civilizačních", multigenně podmíněných chorob
Investor: Ministry of Education, Youth and Sports of the CR, Molecular pathophysiology of selected multigenic related to civilization diseases
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