HONZÍKOVÁ, Nataša, Bořivoj SEMRÁD, Bohumil FIŠER and Růžena LÁBROVÁ. Baroreflex sensitivity determined by spectral method and heart rate variability, and two-years mortality in patients after myocardial infarction. Physiological Research. Praha: Institute of Physiology Academy of Sci., 2000, vol. 49, No 6, p. 643-650. ISSN 0862-8408.
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Basic information
Original name Baroreflex sensitivity determined by spectral method and heart rate variability, and two-years mortality in patients after myocardial infarction.
Name in Czech Citlivost baroreflexu stanovená spektrální metodou a variabilita tepové frekvence, mortalita pacientů dva roky po infartu myokardu
Authors HONZÍKOVÁ, Nataša (203 Czech Republic, guarantor), Bořivoj SEMRÁD (203 Czech Republic), Bohumil FIŠER (203 Czech Republic) and Růžena LÁBROVÁ (203 Czech Republic).
Edition Physiological Research, Praha, Institute of Physiology Academy of Sci. 2000, 0862-8408.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30105 Physiology
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 1.366
RIV identification code RIV/00216224:14110/00:00002701
Organization unit Faculty of Medicine
UT WoS 000166656600003
Keywords in English Baroreflex sensitivity; spectral analysis; myocardial infarction; cardiac death; risk stratification.
Tags baroreflex sensitivity, cardiac death, Myocardial infarction, risk stratification., spectral analysis
Changed by Changed by: prof. MUDr. Nataša Honzíková, CSc., učo 1700. Changed: 17/6/2009 14:44.
Abstract
The impact of an autonomic dysfunction (AD) on mortality in patients after myocardial infarction was evaluated. We examined 162 patients (20 died in two years after myocardial infarction). Baroreflex sensitivity BRS<3ms/mmHg (spectral analysis of spontaneous fluctuations of systolic blood pressure and cardiac intervals) and/or SDNN index<30ms (from 24-hour ECG recording) were taken as markers of AD. The risk stratification was performed according to the number of following standard risk factors (SRF): ejection fraction;40%, positive late potentials and presence of ventricular extrasystoles;10/hour. In 92 patients without SRF, there was no difference in mortality between patients with AD (4%) and without AD (4.5%). In 6 patients with three SRF, mortality was 66.6%. Of 64 patients with one or two SRF, 32 had AD. Mortality was 6.25% in patients without AD and 31.2% in those with AD (p<0.025). AD increased five times the two years mortality in patients with moderate risks.
Abstract (in Czech)
Vliv autonomní dysfunkce na mortalitu pacientů po infarktu myokardu byla studována u 162 pacientů (20 zemřelo během dvou let po IM).Riziková stratifikace byla hodnocena pro autonomní dysfunkci(citlivost baroreflexu, variabilitu tepové frekvence) a pro ejekční frakci, pozdní potenciály a počet extrasystol za hodinu. Autonomní dysfunkce zvýšila mortalitu šestkrát.
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