J 2000

Baroreflex sensitivity determined by spectral method and heart rate variability, and two-years mortality in patients after myocardial infarction.

HONZÍKOVÁ, Nataša, Bořivoj SEMRÁD, Bohumil FIŠER and Růžena LÁBROVÁ

Basic information

Original name

Baroreflex sensitivity determined by spectral method and heart rate variability, and two-years mortality in patients after myocardial infarction.

Name in Czech

Citlivost baroreflexu stanovená spektrální metodou a variabilita tepové frekvence, mortalita pacientů dva roky po infartu myokardu

Authors

HONZÍKOVÁ, Nataša (203 Czech Republic, guarantor), Bořivoj SEMRÁD (203 Czech Republic), Bohumil FIŠER (203 Czech Republic) and Růžena LÁBROVÁ (203 Czech Republic)

Edition

Physiological Research, Praha, Institute of Physiology Academy of Sci. 2000, 0862-8408

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30105 Physiology

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 1.366

RIV identification code

RIV/00216224:14110/00:00002701

Organization unit

Faculty of Medicine

UT WoS

000166656600003

Keywords in English

Baroreflex sensitivity; spectral analysis; myocardial infarction; cardiac death; risk stratification.
Změněno: 17/6/2009 14:44, prof. MUDr. Nataša Honzíková, CSc.

Abstract

V originále

The impact of an autonomic dysfunction (AD) on mortality in patients after myocardial infarction was evaluated. We examined 162 patients (20 died in two years after myocardial infarction). Baroreflex sensitivity BRS<3ms/mmHg (spectral analysis of spontaneous fluctuations of systolic blood pressure and cardiac intervals) and/or SDNN index<30ms (from 24-hour ECG recording) were taken as markers of AD. The risk stratification was performed according to the number of following standard risk factors (SRF): ejection fraction;40%, positive late potentials and presence of ventricular extrasystoles;10/hour. In 92 patients without SRF, there was no difference in mortality between patients with AD (4%) and without AD (4.5%). In 6 patients with three SRF, mortality was 66.6%. Of 64 patients with one or two SRF, 32 had AD. Mortality was 6.25% in patients without AD and 31.2% in those with AD (p<0.025). AD increased five times the two years mortality in patients with moderate risks.

In Czech

Vliv autonomní dysfunkce na mortalitu pacientů po infarktu myokardu byla studována u 162 pacientů (20 zemřelo během dvou let po IM).Riziková stratifikace byla hodnocena pro autonomní dysfunkci(citlivost baroreflexu, variabilitu tepové frekvence) a pro ejekční frakci, pozdní potenciály a počet extrasystol za hodinu. Autonomní dysfunkce zvýšila mortalitu šestkrát.