ZAHRADNÍČKOVÁ, Eva, Sabina ŠEVČÍKOVÁ, Karel SOUČEK and Jan ŠMARDA. The effects of Fos proteins on myeloid differentiation. In V. Pracovní setkání biochemiků a molekulráních biologů. Brno: Masarykova univerzita, 2001, p. 26. ISBN 80-210-2538-7.
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Basic information
Original name The effects of Fos proteins on myeloid differentiation
Authors ZAHRADNÍČKOVÁ, Eva (203 Czech Republic), Sabina ŠEVČÍKOVÁ (203 Czech Republic), Karel SOUČEK (203 Czech Republic) and Jan ŠMARDA (203 Czech Republic, guarantor).
Edition Brno, V. Pracovní setkání biochemiků a molekulráních biologů, p. 26-26, 2001.
Publisher Masarykova univerzita
Other information
Original language English
Type of outcome Proceedings paper
Field of Study Genetics and molecular biology
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14310/01:00002904
Organization unit Faculty of Science
ISBN 80-210-2538-7
Keywords in English Fos
Tags Fos
Changed by Changed by: prof. RNDr. Jan Šmarda, CSc., učo 1223. Changed: 17/2/2009 05:33.
Abstract
The line of v-myb-transformed chicken monoblasts BM2 is a suitable model for study of myeloid differentiation. These cells proliferate in monoblastic stage and their terminal differentiation steps are blocked. We found that overexpression of v-fos and c-fos causes growth arrest of BM2 cells. To clarify this observation we performed cell cycle analysis. We found that c-Fos partially induces apoptosis while v-Fos rather affects cell cycle of BM2 cells.
Links
MSM 143100008, plan (intention)Name: Genomy a jejich funkce
Investor: Ministry of Education, Youth and Sports of the CR, Genomes and their functions
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