D 2000

Metabolism of iodine in rat tissues is markedly influenced by excessive bromide intake

PAVELKA, Stanislav, Arnošt BABICKÝ and Miloslav VOBECKÝ

Basic information

Original name

Metabolism of iodine in rat tissues is markedly influenced by excessive bromide intake

Authors

PAVELKA, Stanislav (203 Czech Republic, guarantor), Arnošt BABICKÝ (203 Czech Republic) and Miloslav VOBECKÝ (203 Czech Republic)

Edition

Leipzig, Mengen- und Spurenelemente 2000 (Anke M. et al., eds.) [IF=n.a.], p. 196-204, 9 pp. 2000

Publisher

Verlag Harald Schubert

Other information

Language

English

Type of outcome

Stať ve sborníku

Field of Study

30202 Endocrinology and metabolism

Country of publisher

Germany

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14310/00:00003154

Organization unit

Faculty of Science

ISBN

3-929526-61-1

UT WoS

000170131900028

Keywords in English

iodine; bromide; metabolism; rat

Tags

International impact, Reviewed
Změněno: 10/1/2009 15:06, doc. RNDr. Stanislav Pavelka, CSc.

Abstract

V originále

In experiments on rats, a significant influence of an extraordinarily high bromide intake on the metabolism of iodine was established. Very high bromide intake (i) increased the relative weight of the thyroid, notably in animals fed the low-iodine diet, (ii) strikingly decreased the amount of radioiodide accumulated in the thyroid of all animals, (iii) significantly shortened the biological half-life of iodine in the thyroid, etc. These changes were caused, with high probability, by an increase of iodine elimination by kidney due to an excess of bromide.

Links

IAA7011813, research and development project
Name: Vliv nadbytku bromu, jodového deficitu nebo jejich kombinace na metabolismus thyroidních hormonů ve tkáních
NJ6109, research and development project
Name: Interference bromidu z životního prostředí s metabolismem jodu ve štítné žláze a dalších tkáních
Investor: Ministry of Health of the CR, Interference of bromide from the environment with iodine metabolism in the thyroid gland and other tissues