PAVELKA, Stanislav, Arnošt BABICKÝ and Miloslav VOBECKÝ. Metabolism of iodine in rat tissues is markedly influenced by excessive bromide intake. In Mengen- und Spurenelemente 2000 (Anke M. et al., eds.) [IF=n.a.]. Leipzig: Verlag Harald Schubert, 2000, p. 196-204. ISBN 3-929526-61-1.
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Basic information
Original name Metabolism of iodine in rat tissues is markedly influenced by excessive bromide intake
Authors PAVELKA, Stanislav (203 Czech Republic, guarantor), Arnošt BABICKÝ (203 Czech Republic) and Miloslav VOBECKÝ (203 Czech Republic).
Edition Leipzig, Mengen- und Spurenelemente 2000 (Anke M. et al., eds.) [IF=n.a.], p. 196-204, 9 pp. 2000.
Publisher Verlag Harald Schubert
Other information
Original language English
Type of outcome Proceedings paper
Field of Study 30202 Endocrinology and metabolism
Country of publisher Germany
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14310/00:00003154
Organization unit Faculty of Science
ISBN 3-929526-61-1
UT WoS 000170131900028
Keywords in English iodine; bromide; metabolism; rat
Tags bromide, iodine, metabolism, rat
Tags International impact, Reviewed
Changed by Changed by: doc. RNDr. Stanislav Pavelka, CSc., učo 313. Changed: 10/1/2009 15:06.
Abstract
In experiments on rats, a significant influence of an extraordinarily high bromide intake on the metabolism of iodine was established. Very high bromide intake (i) increased the relative weight of the thyroid, notably in animals fed the low-iodine diet, (ii) strikingly decreased the amount of radioiodide accumulated in the thyroid of all animals, (iii) significantly shortened the biological half-life of iodine in the thyroid, etc. These changes were caused, with high probability, by an increase of iodine elimination by kidney due to an excess of bromide.
Links
IAA7011813, research and development projectName: Vliv nadbytku bromu, jodového deficitu nebo jejich kombinace na metabolismus thyroidních hormonů ve tkáních
NJ6109, research and development projectName: Interference bromidu z životního prostředí s metabolismem jodu ve štítné žláze a dalších tkáních
Investor: Ministry of Health of the CR, Interference of bromide from the environment with iodine metabolism in the thyroid gland and other tissues
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