Adsorptive Stripping Analysis of DNA with Admittance Detection

JELEN, František, Vladimír VETTERL, Petr BĚLUŠA and Stanislav HASOŇ. Adsorptive Stripping Analysis of DNA with Admittance Detection. Electroanalysis. Weinheim: Wiley-VCH Verlag GmbH, 2000, vol. 12, No 12, p. 987-992. ISSN 1040-0397.

Basic information

• Original name: Adsorptive Stripping Analysis of DNA with Admittance Detection
• Authors: JELEN, František, Vladimír VETTERL (203 Czech Republic, guarantor), Petr BĚLUŠA and Stanislav HASOŇ.
• Edition: Electroanalysis, Weinheim, Wiley-VCH Verlag GmbH, 2000, 1040-0397.

Other information

• Original language: English
• Type of outcome: Article in a journal
• Field of Study: 10610 Biophysics
• Country of publisher: Germany
• Confidentiality degree: is not subject to a state or trade secret
• Impact factor: Impact factor: 1.972
• RIV identification code: RIV/00216224:14310/00:00003158
• Organization unit: Faculty of Science
• Keywords in English: voltammetric analysis; DNA; admittance measurements; DNA damage
• Tags: admittance measurements, DNA, DNA damage, voltammetric analysis

Abstract

Native, denatured and damaged calf thymus DNA was studied by admittance measurement using hanging mercury drop electrode. The obtained results suggest that in damaged regions of double stranded native DNA the bases are accesible for the interaction with the electrode producing peak 3 without passing through the potential region U around -1.2 V, where double stranded DNA is supposed to be slowly opened.

Links

• IAA4004002, research and development project: Name: Struktura a interakce nukleových kyselin a polypeptidů na površích kovů

Investor: Academy of Sciences of the Czech Republic, Structure and Interaction of Nucleic Acids on Metal Surfaces

• IAA4004702, research and development project: Name: Adsorpce bazí, nukleosidů, nukleotidů a polynukleotidů na elektrodách

Investor: Academy of Sciences of the Czech Republic, Adsorption of bases, nucleosides, nucleotides and polynucleotides on electrods