Detailed Information on Publication Record
2000
Effect of very high bromide intake on iodine metabolism in the rat
PAVELKA, Stanislav, Arnošt BABICKÝ and Miloslav VOBECKÝBasic information
Original name
Effect of very high bromide intake on iodine metabolism in the rat
Authors
PAVELKA, Stanislav (203 Czech Republic, guarantor), Arnošt BABICKÝ (203 Czech Republic) and Miloslav VOBECKÝ (203 Czech Republic)
Edition
Chemické Listy [IF=0.278 (1999)], 2000, 0009-2770
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30202 Endocrinology and metabolism
Country of publisher
Czech Republic
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 0.278
RIV identification code
RIV/00216224:14310/00:00003161
Organization unit
Faculty of Science
Keywords in English
bromide; iodine; metabolism; rat
Tags
Tags
International impact, Reviewed
Změněno: 10/1/2009 15:14, doc. RNDr. Stanislav Pavelka, CSc.
Abstract
V originále
The influence of an enhanced bromide intake on the uptake of 131-I by the thyroid and various organs and tissues of rats, on the magnitude of the whole-body biological half-life of iodine, and on the body weight and prosperity of rats was followed with the help of radionuclide tracer techniques. Based on the results obtained, we conclude that a high level of bromide in the organism can obviously influence the iodine metabolism in two parallel ways: by a competitive inhibition of iodide accumulation in the thyroid, and by accelerating the iodine excretion by the kidney.
Links
IAA7011813, research and development project |
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NJ6109, research and development project |
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