Detailed Information on Publication Record
2000
Distribution and kinetics of exogenous bromide in the rat
PAVELKA, Stanislav, Arnošt BABICKÝ, Miloslav VOBECKÝ and Jaroslav LENERBasic information
Original name
Distribution and kinetics of exogenous bromide in the rat
Authors
PAVELKA, Stanislav (203 Czech Republic, guarantor), Arnošt BABICKÝ (203 Czech Republic), Miloslav VOBECKÝ (203 Czech Republic) and Jaroslav LENER
Edition
Chemické Listy [IF=0.278 (1999)], 2000, 0009-2770
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30105 Physiology
Country of publisher
Czech Republic
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 0.278
RIV identification code
RIV/00216224:14310/00:00003162
Organization unit
Faculty of Science
Keywords in English
distribution; kinetics; bromide; rat
Tags
Tags
International impact, Reviewed
Změněno: 10/1/2009 15:16, doc. RNDr. Stanislav Pavelka, CSc.
Abstract
V originále
The distribution of 82-Br-bromide in 15 various organs and tissues of rats has been determined at different times after the application of Na82-Br, either by subcutaneous injection or by continuous administration in the drinking water. Moreover, biological half-lives of bromine in these organs and tissues, in addition to the whole-body half-life, were determined by measuring the radioactive concentration of 82-Br in samples of tissues collected at the time intervals of 12-396 h from animals that continuously (up to 17 d) received 82-Br-bromide in their drinking water. A remarkably high concentration of 82-Br was found in the skin which represented, because of its large mass, the most abundant depot of bromide in the body of rats. In addition, significant correlation between the values of the steady-state concentration of bromide and of the biological half-life of bromine in the particular tissue was found for most tissues, except for liver.
Links
| IAA7011813, research and development project |
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| NJ6109, research and development project |
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