ZELENKOVÁ, Olga, Eva HADAŠOVÁ, Marie TOMANDLOVÁ, Jana NOVÁKOVÁ and Jana VINKLEROVÁ. Changes of CYP2D6 acitivity in rats after drugs of abuse medication. Homeostasis. Milano, Italy: C.I.A.N.S., 2001, vol. 40, No 6, p. 258-260. ISSN 0960-7560.
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Basic information
Original name Changes of CYP2D6 acitivity in rats after drugs of abuse medication
Authors ZELENKOVÁ, Olga, Eva HADAŠOVÁ, Marie TOMANDLOVÁ, Jana NOVÁKOVÁ and Jana VINKLEROVÁ.
Edition Homeostasis, Milano, Italy, C.I.A.N.S. 2001, 0960-7560.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30104 Pharmacology and pharmacy
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14110/01:00004144
Organization unit Faculty of Medicine
Keywords in English CYP2D6; drugs of abuse; metabolism; inhibition
Tags CYP2D6, drugs of abuse, inhibition, metabolism
Changed by Changed by: MUDr. Olga Starobová, Ph.D., učo 2489. Changed: 26/11/2001 11:51.
Abstract
The aim of the study was to establish the influence of long term medication of metamphetamine on the cytoshrome P450 2D1/6 activity in rats in "i.v. self-administration" model.Insignificant decrease in the enzyme activity was recorded.
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