J 2001

Baroreflex sensitivity and body growth parameters in children and adolescents

NOVÁKOVÁ, Zuzana, Nataša HONZÍKOVÁ, Eva ZÁVODNÁ, Hana HRSTKOVÁ, Petra VÁCLAVKOVÁ et. al.

Basic information

Original name

Baroreflex sensitivity and body growth parameters in children and adolescents

Authors

NOVÁKOVÁ, Zuzana (203 Czech Republic, guarantor), Nataša HONZÍKOVÁ (203 Czech Republic), Eva ZÁVODNÁ (203 Czech Republic), Hana HRSTKOVÁ (203 Czech Republic) and Petra VÁCLAVKOVÁ (203 Czech Republic)

Edition

Experimental and Clinical Cardiology, Canada, Pulsus Group Inc. 2001, 0160-9289

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30105 Physiology

Country of publisher

Canada

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 1.008

RIV identification code

RIV/00216224:14110/01:00004186

Organization unit

Faculty of Medicine

Keywords in English

Age; Baroreflex sensitivity; Growth; Height; Spectral analysis; Weight.
Změněno: 22/6/2009 09:35, MUDr. Zuzana Nováková, Ph.D.

Abstract

V originále

OBJECTIVE:To determine the relationship between the baroreflex sensitivity expressed in ms/mmHg (BRS) and in Hz/mmHg (BRSf) and the body growth parameters. METHODS: Two hundred and one children and adolescents aged 10-21 years were examined. This population was analysed as a whole and subsequently was divided into 2 groups: group A - normotensive control (healthy, number of subjects n=154), group B - children with systolic casual blood pressure on primary diagnosis was > 140 mmHg (in 3 measurements at least one week apart, n=47). These groups were divided into subgroups according to the age. BRS and BRSf were determined by spectral analysis of blood pressure and pulse interval variability (5 minute records by Finapres, metronome controlled breathing at frequency of 0.33 Hz). The parameters of body growth (body height, weight, body mass index - BMI) were assessed. Correlation coefficient (Spearman) was calculated between pairs of all parameters (age, pulse interval - PI, BRS, BRSf, height, weight, BMI) for the whole group, groups A, B and for subgroups related to the age. RESULTS: BRS did not correlate with age; it correlated with PI in whole population, in groups A,B and also in age-related subgroups. BRS correlated only exceptionally either with weight, height and/or BMI in the oldest followed subjects (aged 17-19), but there was no correlation with the groups A,B and also with the whole study population. BRSf correlated significantly (p<0.01) with age. It was pulse interval independent for group A and also age-related subgroups. BRSf correlated with weight, height, BMI for normotensive group and for whole population, but not for age-related subgroups. CONCLUSION: BRS (which is mean pulse interval related parameter) does not correlate with age. On the contrary, BRSf (which is mean pulse interval independent) decreases with age significantly. Significant relationship between BRSf and parameters of body growth is related to the age.