ŽÍDEK, Lukáš and Miroslav ŘEZÁČ. Kinetics of inhibition of horse liver alcohol-dehydrogenase by p-methylbenzyl hydroperoxide. Journal of Enzyme Inhibition. Reading: Harwood Acad. Publ. GmbH, 1993, vol. 7, No 3, p. 191-197. ISSN 8755-5093.
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Basic information
Original name Kinetics of inhibition of horse liver alcohol-dehydrogenase by p-methylbenzyl hydroperoxide
Authors ŽÍDEK, Lukáš and Miroslav ŘEZÁČ.
Edition Journal of Enzyme Inhibition, Reading, Harwood Acad. Publ. GmbH, 1993, 8755-5093.
Other information
Type of outcome Article in a journal
Confidentiality degree is not subject to a state or trade secret
Organization unit Faculty of Science
UT WoS A1993MM16800004
Keywords in English HORSE LIVER ALCOHOL DEHYDROGENASE; P-METHYLBENZYL HYDROPEROXIDE
Tags HORSE LIVER ALCOHOL DEHYDROGENASE, P-METHYLBENZYL HYDROPEROXIDE
Changed by Changed by: prof. Mgr. Lukáš Žídek, Ph.D., učo 38990. Changed: 26/2/2003 07:36.
Abstract
The complex kinetic behaviour of p-methylbenzyl hydroperoxide in its inhibitory action on horse liver alcohol dehydrogenase was examined. The kinetic patterns are markedly different at very low (<10(-8) M) and high (>10(-7) M) hydroperoxide concentrations. In both cases very low inhibition constants (4nM and 14nM, respectively) were found. A possible mechanistic model based on these results is discussed.
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