Differential recognition of DNA modified by antitumor cisplatin and its clinically ineffective trans isomer by tumor suppressor protein p53

KAŠPÁRKOVÁ, Jana, Šárka POSPÍŠILOVÁ and Viktor BRABEC. Differential recognition of DNA modified by antitumor cisplatin and its clinically ineffective trans isomer by tumor suppressor protein p53. In Journal of Biological Chemistry. 2001, p. 16064-16069.

Basic information

Original name

Differential recognition of DNA modified by antitumor cisplatin and its clinically ineffective trans isomer by tumor suppressor protein p53

Authors

KAŠPÁRKOVÁ, Jana, Šárka POSPÍŠILOVÁ and Viktor BRABEC

Edition

Journal of Biological Chemistry, p. 16064-16069, 2001

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Other information

Type of outcome

Stať ve sborníku

Confidentiality degree

není předmětem státního či obchodního tajemství

Organization unit

Faculty of Science

Keywords in English

DNA; p53; cisplatina; cytostatika; mechanismus

Tags

cisplatina, cytostatika, DNA, mechanismus, p53

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Links

GA305/99/0695, research and development project

Name: Ovlivnění konformace DNA protinádorově účinnými komplexy kovů. Vztah k vývoji nových cytostatik.