ŽOURKOVÁ, Alexandra, Eva HADAŠOVÁ and Miroslav ROBEŠ. Vztah mezi EM a PM CYP 2D6 ve výskytu sexuálních dysfunkcí (The relation between EM and PM CYP 2D6 in sexual dysfunction). Psychiatrie. Praha: Tigis, 2001, vol. 5, Suppl. 2, p. 148-149. ISSN 1211-7579.
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Basic information
Original name Vztah mezi EM a PM CYP 2D6 ve výskytu sexuálních dysfunkcí
Name (in English) The relation between EM and PM CYP 2D6 in sexual dysfunction
Authors ŽOURKOVÁ, Alexandra (203 Czech Republic), Eva HADAŠOVÁ (203 Czech Republic) and Miroslav ROBEŠ (203 Czech Republic).
Edition Psychiatrie, Praha, Tigis, 2001, 1211-7579.
Other information
Original language Czech
Type of outcome Article in a journal
Field of Study 30000 3. Medical and Health Sciences
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14110/01:00004244
Organization unit Faculty of Medicine
Keywords in English sexual dysfunctions; paroxetine; CYP 2D6; poor metabolizer; extenzive metabolizer
Tags CYP 2D6, extenzive metabolizer, paroxetine, poor metabolizer, sexual dysfunctions
Changed by Changed by: prof. MUDr. Alexandra Žourková, CSc., učo 81. Changed: 2/10/2003 13:50.
Abstract
Práce se zabývá výskytem sexuálních dysfunkcí při léčbě paroxetinem v závislosti na kativitě CYP2D6. V souboru dvaceti pacientů čtrnáct z nich trpělo sexuální dysfunkcí. Statistické srovnání (Mann-Whietney test) položek škál ASEX, UKU, SFM/SFŽ dokázalo při užití dotazníku SFŽ statistickou signifikanci v položkách lubrikace, libido a sebehodnocení u žen se sníženou metabolickou kapacitou CYP 2D6.
Abstract (in English)
The paper deals with th incidence of sexual dysfunction in treatment by paroxetine depending on CYP 2D6 activity. The group of 20 patients included 14 with sexual dysfunction. The statistic comparison (by the Mann-Whitney test) of ASEX UKU and SFM/SFŽ scale items revealed a statistic significant women with recuded CYP 2D6 metabolic capacity in the lubrical on, sexual desire, and self-evaluation items.
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