Detailed Information on Publication Record
2001
TGF-beta1 gene polymorphisms
BUČKOVÁ, Dana, Lydie IZAKOVIČOVÁ HOLLÁ, Petr BENEŠ, Vladimír ZNOJIL, Jiří VÁCHA et. al.Basic information
Original name
TGF-beta1 gene polymorphisms
Authors
BUČKOVÁ, Dana (203 Czech Republic, guarantor), Lydie IZAKOVIČOVÁ HOLLÁ (203 Czech Republic), Petr BENEŠ (203 Czech Republic), Vladimír ZNOJIL (203 Czech Republic) and Jiří VÁCHA (203 Czech Republic)
Edition
Allergy, Denmark, Munksgaard International Publishers, 2001, 0105-4538
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
Genetics and molecular biology
Country of publisher
Denmark
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 2.852
RIV identification code
RIV/00216224:14110/01:00004361
Organization unit
Faculty of Medicine
UT WoS
000172476700031
Keywords in English
gene; polymorphism; allergy; TGF; asthma
Tags
Změněno: 17/6/2009 12:52, prof. MUDr. Lydie Izakovičová Hollá, Ph.D.
Abstract
V originále
Transforming growth factor beta (TGF-beta) is a pleiotropic cytokine with significant anti-inflammatory and immunosuppressive properties. The single base pair polymorphism located at -509 (C/T) in the promoter region of the TGF-beta1 gene was previously shown to be associated with elevated total serum IgE levels. We tested the hypothesis that polymorphic alleles of the TGF-beta1 gene are associated with allergies and asthma.
Links
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