J
2001
Dynamics of clinical response to paroxetine in coherence with CYP 2D6 metabolic status during long-term therapy of depressive disorder.
HADAŠOVÁ, Eva, Alexandra ŽOURKOVÁ and Olga ZELENKOVÁ
Basic information
Original name
Dynamics of clinical response to paroxetine in coherence with CYP 2D6 metabolic status during long-term therapy of depressive disorder.
Edition
South African Journal of Science, Johannesburg, 2001
Other information
Type of outcome
Článek v odborném periodiku
Field of Study
30000 3. Medical and Health Sciences
Country of publisher
South Africa
Confidentiality degree
není předmětem státního či obchodního tajemství
RIV identification code
RIV/00216224:14110/01:00004765
Organization unit
Faculty of Medicine
Keywords in English
Genetic polymorphism; cytochrome P450; SSRI; psychiatry; sexual disorder
V originále
Long-term therapy with SSRI antidepressants can evoke adverse effects including sexual disorders which may be more pronounced in patients with decreased activity of CYP 2D6, either given by the defect of the enzyme expression or evoked by previous treatment with enzyme inhibitors.
Links
| NF6159, research and development project | | Name: Dynamika fenotypu CYP 2D6 u pacientů léčených paroxetinem ve vztahu ke klinickým korelátům. | | Investor: Ministry of Health of the CR, Phenotype dynamics in patient treated by paroxetine regarding the clinical correlates |
|
Displayed: 21/10/2024 20:52