RAITERI, Roberto, Massimo GRATTAROLA, Hans-Jurgen BUTT and Petr SKLÁDAL. Micromechanical cantilever-based biosensors. Sensors and Actuators B Chemical. Amsterdam (Holandsko): Elsevier, 2001, vol. 79, No 2, p. 115-126. ISSN 0925-4005.
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Basic information
Original name Micromechanical cantilever-based biosensors
Authors RAITERI, Roberto, Massimo GRATTAROLA, Hans-Jurgen BUTT and Petr SKLÁDAL.
Edition Sensors and Actuators B Chemical, Amsterdam (Holandsko), Elsevier, 2001, 0925-4005.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10610 Biophysics
Country of publisher Netherlands
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 1.440
RIV identification code RIV/00216224:14310/01:00004850
Organization unit Faculty of Science
UT WoS 000171679600005
Keywords in English microcantilever; immunosensor; albumin; immobilization; biosensor
Tags albumin, biosensor, immobilization, immunosensor, microcantilever
Changed by Changed by: prof. RNDr. Petr Skládal, CSc., učo 2202. Changed: 5/12/2001 10:37.
Abstract
The merging of silicon microfabrication techniques with surface functionalization biochemistry offers new exciting opportunities in developing microscopic biomedical analysis devices with unique characteristics. Micro-mechanical transducers for chemical and biosensing applications represent one possibility. Microcantilevers can transduce a chemical signal into a mechanical motion with high sensitivity. In this review we summarize how cantilever-based sensors can be operated, and their working principle is presented in few selected biosensing experiments which have been performed recently in our groups in the study of biotin-streptavidin and antigen-antibody interactions, and specific surface charge development of organic molecules. We also discuss the advantages of this novel technique as well as its potentials.
Links
GA203/96/0070, research and development projectName: Sledování bioafinitních interakcí ve vodě a v organických rozpouštědlech použitím piezoelektrických krystalů
Investor: Czech Science Foundation, Monitoring of bioaffinity interactions in water and in organic solvents using piezoelectric crystals
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