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@article{379333,
author = {Svíženská, Ivana and Klusáková, Ilona and Ghalib, Nabil Ahmed and Dubový, Petr},
article_location = {Holandsko},
article_number = {4},
language = {eng},
issn = {0018-2214},
journal = {The Histochemical Journal},
title = {Immunohistochemical differences in the ECM content alongside afferent and motor axons in relation to the position of the dorsal root ganglion},
volume = {33},
year = {2001}
}
TY - JOUR
ID - 379333
AU - Svíženská, Ivana - Klusáková, Ilona - Ghalib, Nabil Ahmed - Dubový, Petr
PY - 2001
TI - Immunohistochemical differences in the ECM content alongside afferent and motor axons in relation to the position of the dorsal root ganglion
JF - The Histochemical Journal
VL - 33
IS - 4
SP - 247
EP - 247
PB - Kluwer Academic Publishers
SN - 00182214
N2 - The extracellular matrix (ECM) provides signalling cues that regulate cell behaviour during peripheral nerve formation and homeostasis. Composition of the ECM is the major determinant of the microenvironmental condition that controls the nerve regeneration. To reveal different microenvironmental conditions for motor and afferent axons we have analysed immunohistochemically some ECM components and adhesion molecules (laminin-2, -3, fibronectin, thrombospondin, tenascin, chondroitin sulphate, and HNK-1) in the spinal roots and branches of the spinal nerve. The results of quantitative immunofluorescence analysis suggest some differences in the content of ECM along the afferent and motor axons that could be involved in the origin of different conditions for the axon regrowth after injury of the dorsal and ventral roots as well as the spinal nerves.
ER -
SVÍŽENSKÁ, Ivana, Ilona KLUSÁKOVÁ, Nabil Ahmed GHALIB a Petr DUBOVÝ. Immunohistochemical differences in the ECM content alongside afferent and motor axons in relation to the position of the dorsal root ganglion. \textit{The Histochemical Journal}. Holandsko: Kluwer Academic Publishers, roč.~33, č.~4, s.~247-248. ISSN~0018-2214. 2001.
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