Relationship between ejection fraction and baroreflex sensitivity in patients after myocardial infarction

HONZÍKOVÁ, Nataša, Bohumil FIŠER and Bořivoj SEMRÁD. Relationship between ejection fraction and baroreflex sensitivity in patients after myocardial infarction. Scripta medica. Brno: Masaryk University in Brno, 2001, vol. 74, No 1, p. 55-59. ISSN 0211-3395.

Basic information

• Original name: Relationship between ejection fraction and baroreflex sensitivity in patients after myocardial infarction
• Authors: HONZÍKOVÁ, Nataša, Bohumil FIŠER and Bořivoj SEMRÁD.
• Edition: Scripta medica, Brno, Masaryk University in Brno, 2001, 0211-3395.

Other information

• Original language: English
• Type of outcome: Article in a journal
• Field of Study: 30105 Physiology
• Country of publisher: Czech Republic
• Confidentiality degree: is not subject to a state or trade secret
• RIV identification code: RIV/00216224:14110/01:00004908
• Organization unit: Faculty of Medicine
• Keywords in English: baroreflex sensitivity; spectral analysis; myocardial infarction; ejection fraction; heart failure
• Tags: baroreflex sensitivity, ejection fraction, Heart failure, Myocardial infarction, spectral analysis

Abstract

The relationship between ejection fraction (EF) and baroreflex sensitivity (BRS in ms/mmHg and BRSf in Hz/mmHg) in 117 patients 7-14 dayes after myocardial infarction was studied. BRS and BRSf were determined by spectral analysis of pulse intervals and blood pressure fluctuation (Finapres, 3 min recording, breathing 0.33 Hz). At EF between 40-70% (n=92), BRS and BRSf remained constant (meanąSD: 5.5ą3.3 ms/mmHg, 0.0077ą0.00511 Hz/mmHg). At EF 30-40% (n=17), lower values of BRS and BRSf were observed (BRS: 58.1ą48.5%, BRSf: 67.5ą54.7% of the values at high EF). The difference between BRS and BRSf was significant (p<0.05). At EF 20-30% (n=8), BRS was 33.9ą23.6% and BRSf was 34.9ą21.3% of the values at high EF. The values of the PI-dependent BRS correspond to the baroreceptor sensitivity and to the activity of the autonomic nervs, which is altered at EF 30-40%. The PI-independent BRSf corresponds only to the baroreceptor sensitivity, which is decreased at very low EF.