J 2001

Relationship between ejection fraction and baroreflex sensitivity in patients after myocardial infarction

HONZÍKOVÁ, Nataša, Bohumil FIŠER and Bořivoj SEMRÁD

Basic information

Original name

Relationship between ejection fraction and baroreflex sensitivity in patients after myocardial infarction

Authors

HONZÍKOVÁ, Nataša, Bohumil FIŠER and Bořivoj SEMRÁD

Edition

Scripta medica, Brno, Masaryk University in Brno, 2001, 0211-3395

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30105 Physiology

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14110/01:00004908

Organization unit

Faculty of Medicine

Keywords in English

baroreflex sensitivity; spectral analysis; myocardial infarction; ejection fraction; heart failure
Změněno: 6/12/2001 13:32, prof. MUDr. Nataša Honzíková, CSc.

Abstract

V originále

The relationship between ejection fraction (EF) and baroreflex sensitivity (BRS in ms/mmHg and BRSf in Hz/mmHg) in 117 patients 7-14 dayes after myocardial infarction was studied. BRS and BRSf were determined by spectral analysis of pulse intervals and blood pressure fluctuation (Finapres, 3 min recording, breathing 0.33 Hz). At EF between 40-70% (n=92), BRS and BRSf remained constant (meanąSD: 5.5ą3.3 ms/mmHg, 0.0077ą0.00511 Hz/mmHg). At EF 30-40% (n=17), lower values of BRS and BRSf were observed (BRS: 58.1ą48.5%, BRSf: 67.5ą54.7% of the values at high EF). The difference between BRS and BRSf was significant (p<0.05). At EF 20-30% (n=8), BRS was 33.9ą23.6% and BRSf was 34.9ą21.3% of the values at high EF. The values of the PI-dependent BRS correspond to the baroreceptor sensitivity and to the activity of the autonomic nervs, which is altered at EF 30-40%. The PI-independent BRSf corresponds only to the baroreceptor sensitivity, which is decreased at very low EF.