HOFER, Michal, Milan POSPÍŠIL, Lenka WEITEROVÁ, Vladimír ZNOJIL, Jiří VÁCHA, Jarmila HOLÁ, Antonín VACEK and Iva PIPALOVÁ. Combination of drugs elevating extracellular adenosine with granulocyte colony-stimulating factor promotes granulopoietic recovery in the murine bone marrow after 5-fluorouracil treatment. Physiological Research. Prague: Czech Academy of Sciences, 2001, vol. 50, March, p. 521-524. ISSN 0862-8408.
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Basic information
Original name Combination of drugs elevating extracellular adenosine with granulocyte colony-stimulating factor promotes granulopoietic recovery in the murine bone marrow after 5-fluorouracil treatment
Authors HOFER, Michal, Milan POSPÍŠIL, Lenka WEITEROVÁ, Vladimír ZNOJIL, Jiří VÁCHA, Jarmila HOLÁ, Antonín VACEK and Iva PIPALOVÁ.
Edition Physiological Research, Prague, Czech Academy of Sciences, 2001, 0862-8408.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30200 3.2 Clinical medicine
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 1.027
RIV identification code RIV/00216224:14110/01:00005027
Organization unit Faculty of Medicine
UT WoS 000172209300009
Changed by Changed by: prof. MUDr. Jiří Vácha, DrSc., učo 1327. Changed: 17/12/2001 09:10.
Abstract
Combined administration of drugs elevating extracellular adenosine, namely dipyridamole and adenosine monophosphate, together with granulocyte colony-stimulating factor was shown to enhance granulopoietic recovery in the bone marrow of mice treated with 5-fluorouracil. The results might have positive clinical impact. The adjunct use of drugs elevating extracellular adenosine might reduce the cost expenditure of therapy with granulocyte colony-stimulating factor.
Links
GA306/99/0027, research and development projectName: Posílení účinnosti G-CSF receptorovým působením adenosinu: testování možného klinického využití na myším modelu
Investor: Czech Science Foundation, Enhancement of G-CSF action by adenosine signalling: testing of its potential clinical use in murine models
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