Je víno zdravé? Resveratrol ano

PAZOUREK, Jiří and Josef HAVEL. Je víno zdravé? Resveratrol ano (Is wine healthful? Resveratrol is.). Praha: Vesmír, 2001, 2 pp. Vesmír 80(2), 374.

Basic information

• Original name: Je víno zdravé? Resveratrol ano
• Name (in English): Is wine healthful? Resveratrol is.
• Authors: PAZOUREK, Jiří (203 Czech Republic, guarantor) and Josef HAVEL (203 Czech Republic).
• Edition: Praha, 2 pp. Vesmír 80(2), 374, 2001.
• Publisher: Vesmír

Other information

• Original language: Czech
• Type of outcome: Book on a specialized topic
• Field of Study: 10406 Analytical chemistry
• Country of publisher: Czech Republic
• Confidentiality degree: is not subject to a state or trade secret
• RIV identification code: RIV/00216224:14310/01:00006057
• Organization unit: Faculty of Science
• Keywords in English: resveratrol; wine; polyphenols
• Tags: Polyphenols, resveratrol, Wine

Abstract

Polyfenolické látky ve víně mají významné biologické účinky: a) Antioxidační efekt Bylo klinicky zjištěno, že konzumace červeného vína, vede ke zvýšení krevní hladiny HDL (high density lipids) b) Protirakovinný efekt V roce 1997 zveřejnil tým dr. Pezzuta z illinoiské Univerzity z Chicaga (USA) článek o protirakovinném působení resveratrolu. Bylo zjistěno in vitro i in vivo, že všechny fáze rakovinného procesu byly inhibovány resveratrolem, jehož přítomnost zvyšovala koncentraci enzymu chinon-reduktázy, která metabolicky detoxikuje karcinogeny. Resveratrol také vykazoval protisrážlivý efekt krve a inhiboval aktivitu cyklooxygenázy-1 (COX-1) a hyperoxydáz, navíc u myší, kterým byl podáván karcinogen, též inhiboval rakovinný proces.

Abstract (in English)

Polyfenolic compunds in wine exhibit important biological effects: a) Antioxidation effect It has been clinically proved that consumption of red wine leads to increase in level of HDL (high density lipids)in blood. b) Anticancer effect In 1997 the team of dr. Pezzuto (Illinois University, Chicago, USA) has published an article about anticancer effect of resveratrolu. It has been found in vitro and in vivo, that all stages of the cancer process have been inhibited by resveratrol. Its presence increased concentration of enzyme of quinone-reductase, which metabolically detoxicates carcinogens. Resveratrol also exhibited antiprecipitation effect in blood and inhibited the activity of cyclooxygenase-1 (COX-1) and hyperoxydases. Moreover, mice fed with a carcinogen, resveratrol inhibited the cancer progress.

Links

• MSM 143100011, plan (intention): Name: Struktura a vazebné poměry, vlastnosti a analýza syntetických a přírodních molekulových ansamblů

Investor: Ministry of Education, Youth and Sports of the CR, Structure and character of bonding, properties and analysis of synthetic and natural molecular ensembles