15N NMR Spectroscopy in Structural Analysis

J 2002

15N NMR Spectroscopy in Structural Analysis

MAREK, Radek and Antonín LYČKA

Basic information

Original name

15N NMR Spectroscopy in Structural Analysis

Authors

MAREK, Radek (203 Czech Republic, guarantor, belonging to the institution) and Antonín LYČKA (203 Czech Republic)

Edition

Current Organic Chemistry, BR Hilversum, Bentham Science Publishers, 2002, 1385-2728

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10401 Organic chemistry

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

DOI: 10.2174/1385272023374643

Impact factor

Impact factor: 2.240

RIV identification code

RIV/00216224:14310/02:00005515

Organization unit

Faculty of Science

DOI

http://dx.doi.org/10.2174/1385272023374643

Keywords in English

15N NMR; structural analysis; correlation spectroscopy

Abstract

V originále

The implementation of both the directly and the inversely detected 15N NMR techniques at the natural abundance level of the 15N isotope is demonstrated for a diverse array of structural problems in organic chemistry. Following the application of 15N NMR to the elucidation of the structures of natural compounds and synthetic products, the 15N-detected electron distribution in such molecules and following their reactions with other molecules and ions is discussed. A significant part of the 15N structural analysis is devoted to the description of tautomers, rotamers, conformers, configurational isomers, and regioisomers. The changes in the 15N parameters induced in structurally related compounds are described briefly. At present, the optimum probe-tube-sample configuration makes it possible to acquire inverse-detected 1H-15N correlation spectra on samples, where the total available sample is limited to amounts of < 1 mg (for molecules [sim] <1000 Da and magnetic fields [sim] > 400 MHz). 15N NMR spectroscopy at the natural abundance level of 15N nuclei has become a powerful tool which has substantially extended the analytical arsenal of organic chemists.

Links

LN00A016, research and development project

Name: BIOMOLEKULÁRNÍ CENTRUM

Investor: Ministry of Education, Youth and Sports of the CR, Biomolecular Center

Citovat

MAREK, Radek and Antonín LYČKA. 15N NMR Spectroscopy in Structural Analysis. Current Organic Chemistry. BR Hilversum: Bentham Science Publishers, 2002, vol. 6, No 1, p. 35-66. ISSN 1385-2728. Available from: https://dx.doi.org/10.2174/1385272023374643.

@article{396401,
   author = {Marek, Radek and Lyčka, Antonín},
   article_location = {BR Hilversum},
   article_number = {1},
   doi = {http://dx.doi.org/10.2174/1385272023374643},
   keywords = {15N NMR; structural analysis; correlation spectroscopy},
   language = {eng},
   issn = {1385-2728},
   journal = {Current Organic Chemistry},
   title = {15N NMR Spectroscopy in Structural Analysis},
   url = {http://dx.doi.org/10.2174/1385272023374643},
   volume = {6},
   year = {2002}
}

TY  - JOUR
ID  - 396401
AU  - Marek, Radek - Lyčka, Antonín
PY  - 2002
TI  - 15N NMR Spectroscopy in Structural Analysis
JF  - Current Organic Chemistry
VL  - 6
IS  - 1
SP  - 35
EP  - 35
PB  - Bentham Science Publishers
SN  - 13852728
KW  - 15N NMR
KW  - structural analysis
KW  - correlation spectroscopy
UR  - http://dx.doi.org/10.2174/1385272023374643
N2  - The implementation of both the directly and the inversely detected 15N NMR techniques at the natural abundance level of the 15N isotope is demonstrated for a diverse array of structural problems in organic chemistry. Following the application of 15N NMR to the elucidation of the structures of natural compounds and synthetic products, the 15N-detected electron distribution in such molecules and following their reactions with other molecules and ions is discussed. A significant part of the 15N structural analysis is devoted to the description of tautomers, rotamers, conformers, configurational isomers, and regioisomers. The changes in the 15N parameters induced in structurally related compounds are described briefly. At present, the optimum probe-tube-sample configuration makes it possible to acquire inverse-detected 1H-15N correlation spectra on samples, where the total available sample is limited to amounts of < 1 mg (for molecules [sim] <1000 Da and magnetic fields [sim] > 400 MHz). 15N NMR spectroscopy at the natural abundance level of 15N nuclei has become a powerful tool which has substantially extended the analytical arsenal of organic chemists.
ER  -

MAREK, Radek and Antonín LYČKA. 15N NMR Spectroscopy in Structural Analysis. \textit{Current Organic Chemistry}. BR Hilversum: Bentham Science Publishers, 2002, vol.~6, No~1, p.~35-66. ISSN~1385-2728. Available from: https://dx.doi.org/10.2174/1385272023374643.

Detailed Information on Publication Record