WOZNICOVÁ, Vladana and Miroslav VOTAVA. Western blot determination of IgG avidity in primary and secondary syphilis. Scripta medica (Brno). Brno: MU Brno, 2001, vol. 74, No 5, p. 355-362. ISSN 1211-3395.
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Basic information
Original name Western blot determination of IgG avidity in primary and secondary syphilis.
Name in Czech Stanovení avidity IgG pomocí westernblotu u případů primární a sekundární syfilidy
Name (in English) Western blot determination of IgG avidity in primary and secondary syphilis.
Authors WOZNICOVÁ, Vladana (203 Czech Republic, guarantor) and Miroslav VOTAVA (203 Czech Republic).
Edition Scripta medica (Brno), Brno, MU Brno, 2001, 1211-3395.
Other information
Original language Czech
Type of outcome Article in a journal
Field of Study 10600 1.6 Biological sciences
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14110/01:00030459
Organization unit Faculty of Medicine
Keywords in English low-avidity IgG; syphilis; Western blot
Tags low-avidity IgG, syphilis, Western blot
Changed by Changed by: doc. MUDr. Vladana Woznicová, Ph.D., učo 606. Changed: 18/6/2009 14:08.
Abstract
IgG avidity to p15.5 kD, p17 kD, and p47 kD antigens of Treponema pallidum was analysed by a new avidity assay termed avidity Western blot. Group I consisted of sera from 27 patients with primary and secondary syphilis, group II comprised 10 subjects with latent syphilis. Low-avidity antibodies were directed against the p17 kD and p47 kD antigens in group I and against the p47 kD antigen in group II. No low-avidity IgG antibodies were detected by ELISA, a routine method for avidity assessment.
Abstract (in English)
IgG avidity to p15.5 kD, p17 kD, and p47 kD antigens of Treponema pallidum was analysed by a new avidity assay termed avidity Western blot. Group I consisted of sera from 27 patients with primary and secondary syphilis, group II comprised 10 subjects with latent syphilis. Low-avidity antibodies were directed against the p17 kD and p47 kD antigens in group I and against the p47 kD antigen in group II. No low-avidity IgG antibodies were detected by ELISA, a routine method for avidity assessment.
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