Detailed Information on Publication Record
2002
A newly identified single nucleotide polymorphism in the promoter of the matrix metalloproteinase-1 gene
JURAJDA, Michal, Jan MUŽÍK, Lydie IZAKOVIČOVÁ HOLLÁ and Jiří VÁCHABasic information
Original name
A newly identified single nucleotide polymorphism in the promoter of the matrix metalloproteinase-1 gene
Authors
JURAJDA, Michal (203 Czech Republic, guarantor), Jan MUŽÍK (203 Czech Republic), Lydie IZAKOVIČOVÁ HOLLÁ (203 Czech Republic) and Jiří VÁCHA (203 Czech Republic)
Edition
Molecular and Cellular Probes, London, Academic Press Ltd, London, 2002, 0890-8508
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
Genetics and molecular biology
Country of publisher
United Kingdom of Great Britain and Northern Ireland
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 1.269
RIV identification code
RIV/00216224:14110/02:00005661
Organization unit
Faculty of Medicine
UT WoS
000174504100008
Keywords in English
single nucleotide polymorphism; matrix metalloproteinase
Změněno: 17/6/2009 12:46, prof. MUDr. Lydie Izakovičová Hollá, Ph.D.
Abstract
V originále
Matrix metalloproteinase-1 (MMP-1) is a member of the matrix metalloproteinase enzyme family that degrades components of the extracellular matrix. Recent studies have demonstrated several polymorphic sites in the promoter of the MMP-1 gene. A newly identified single nucleotide polymorphism (SNP) at position -519 in the promoter region of the MMP-1 gene is reported. This polymorphism consists in a guanine to adenine substitution. A linkage between polymorphisms -519A/G and -1607 1G/2G was also studied.
Links
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