Detailed Information on Publication Record
2002
Polymorphism 2184A/G in the gene encoding Receptor of Advanced Glycation End products (RAGE) is a newly identified risk factor for diabetic nephropathy
KAŇKOVÁ, Kateřina and Miluše HERTLOVÁBasic information
Original name
Polymorphism 2184A/G in the gene encoding Receptor of Advanced Glycation End products (RAGE) is a newly identified risk factor for diabetic nephropathy
Name in Czech
Polymorfizmus 2184A/G v genu pro Receptor of Advanced Glycation End products (RAGE) je nove identifikovany rizikovy faktor diabeticke nefropatie
Authors
KAŇKOVÁ, Kateřina (203 Czech Republic, guarantor) and Miluše HERTLOVÁ (203 Czech Republic)
Edition
Diabetologia, Germany, Springer Verlag Berlin, 2002, 0012-186X
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30202 Endocrinology and metabolism
Country of publisher
Austria
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 5.136
RIV identification code
RIV/00216224:14110/02:00006122
Organization unit
Faculty of Medicine
UT WoS
000177813601105
Keywords in English
polymorphism; RAGE; diabetic nephropathy
Tags
Změněno: 24/6/2009 15:27, prof. MUDr. Kateřina Kaňková, Ph.D.
V originále
Association of the genetic polymorphism in the Receptor of Advanced Glycation End products (RAGE) gene with diabetic nephropathy (DN) in patients with both type 1 and 2 diabetes mellitus was studied. Significant difference in allele frequencies of the 2184A/G between ESRD subgroup and non-DN group was found (P=0.021, Fisher exact test. Moreover, marginally significant association of allele D with DN was detected for the I/D ACE polymorphism (P= 0.075). The presented data indicate that the 2184A/G polymorphism in the RAGE gene could be regarded as one of genetic risk factors for DN. Association of this polymorphism with susceptibility to develop DN and rate of progression and severity of DN is a subject of ongoing study.
In Czech
Zjistili jsme, ze polymorfizmus 2184A/G v genu pro Receptor of Advanced Glycation End products (RAGE) je nove identifikovany rizikovy faktor diabeticke nefropatie.
Links
| MSM 141100002, plan (intention) |
|