Relation between sexual dysfunctions and CYP 2D6 activity

ŽOURKOVÁ, Alexandra and Eva HADAŠOVÁ. Relation between sexual dysfunctions and CYP 2D6 activity. European psychiatry. Paris, France: Elsevier, 2002, vol. 17, Suppl. 1, p. 190s, 1 pp. ISSN 0924-9338.

Basic information

• Original name: Relation between sexual dysfunctions and CYP 2D6 activity
• Name in Czech: Vztah mezi sexuálními dysfunkcemi a aktivitou CYP 2D6
• Authors: ŽOURKOVÁ, Alexandra (203 Czech Republic, guarantor) and Eva HADAŠOVÁ (203 Czech Republic).
• Edition: European psychiatry, Paris, France, Elsevier, 2002, 0924-9338.

Other information

• Original language: English
• Type of outcome: Article in a journal
• Field of Study: 30000 3. Medical and Health Sciences
• Country of publisher: France
• Confidentiality degree: is not subject to a state or trade secret
• Impact factor: Impact factor: 1.327
• RIV identification code: RIV/00216224:14110/02:00006177
• Organization unit: Faculty of Medicine
• UT WoS: 000177273600742
• Keywords in English: depressive disorder; paroxetine; sexual dysfunctions; CYP 2D6 genotype; CYP 2D6 phenotype
• Tags: CYP 2D6 genotype, CYP 2D6 phenotype, depressive disorder, paroxetine, sexual dysfunctions
• Tags: International impact, Reviewed

Abstract

The frequency and severity of adverse effects related to sex-life were studied in patients with depressive disorder in relationship with their CYP2D6 genotype/phenotype. Subjects in which the CYP 2D6 capacity was decreased due to the long-term paroxetine treatment reported significantly higher occurence of sexual dysfunction as evaluated by the ASEX scale.

Abstract (in Czech)

Studie se zabývá vztahem mezi sexuálními dysfunkcemi a aktivitou CYP 2D6 u sledovaných pacientů

Links

• NF6159, research and development project: Name: Dynamika fenotypu CYP 2D6 u pacientů léčených paroxetinem ve vztahu ke klinickým korelátům.

Investor: Ministry of Health of the CR, Phenotype dynamics in patient treated by paroxetine regarding the clinical correlates