NOVÁKOVÁ, Marie and Jiří MOUDR. Horizontal Bath for Pharmacological Studies in Isolated Multicellular Heart Preparations. In Analysis of Biomedical Signals and Images. 16th ed. Brno: Brno University of Technology, Vutium Press, 2002, p. 240-242. ISBN 80-214-2120-7.
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Basic information
Original name Horizontal Bath for Pharmacological Studies in Isolated Multicellular Heart Preparations
Name in Czech Vodorovná láznička pro farmakologické studie na izolovaných multicelulárních preparátech
Authors NOVÁKOVÁ, Marie (203 Czech Republic, guarantor) and Jiří MOUDR (203 Czech Republic).
Edition 16. vyd. Brno, Analysis of Biomedical Signals and Images, p. 240-242, 2002.
Publisher Brno University of Technology, Vutium Press
Other information
Original language English
Type of outcome Proceedings paper
Field of Study 30105 Physiology
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14110/02:00006179
Organization unit Faculty of Medicine
ISBN 80-214-2120-7
ISSN 1211-412X
UT WoS 000178613000076
Keywords in English multicellular heart preparations; contractility measurements
Tags contractility measurements, multicellular heart preparations
Tags International impact, Reviewed
Changed by Changed by: prof. MUDr. Marie Nováková, Ph.D., učo 1188. Changed: 23/6/2009 18:04.
Abstract
A horizontal bath for studying multicellular heart preparations convenient for pharmacological studies is presented. The technique enables the experimenter to obtain valuable data from multicellular samples of mammalian heart tissue. The preparations can be isolated from different parts of the heart of different species of laboratory animals. Stimulated twitches are recorded using a special software. Several parameters can be calculated from the recordings. This system makes it possible to use one preparation for several, even long lasting experiments and thus to minimise the number of sacrificed animals.
Abstract (in Czech)
V článku je popisována vodorovná láznička sloužící pro farmakologické studie na srdečních multicelulárních preparátech. Umožňuje srovnání srdečních svalů z různých částí (síň vs. komora, pravá vs. levá) za zcela identických experimentálních podmínek.
Links
GA102/01/1494, research and development projectName: Optické snímání akčních potenciálů a jeho využití v kardiologii
Investor: Czech Science Foundation, Optical recording of action potentials and its application in cardiology
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