a 2002

Polymorphisms in inflammatory genes (TNFalpha, TNFbeta and TNFalpha-converting enzyme) in chronic heart failure

GOLDBERGOVÁ, Monika, Lenka ŠPINAROVÁ, Jindřich ŠPINAR, Svatava TSCHÖPLOVÁ, Anna VAŠKŮ et. al.

Basic information

Original name

Polymorphisms in inflammatory genes (TNFalpha, TNFbeta and TNFalpha-converting enzyme) in chronic heart failure

Authors

GOLDBERGOVÁ, Monika (203 Czech Republic, guarantor), Lenka ŠPINAROVÁ (203 Czech Republic), Jindřich ŠPINAR (203 Czech Republic), Svatava TSCHÖPLOVÁ (203 Czech Republic) and Anna VAŠKŮ (203 Czech Republic)

Edition

2002

Other information

Language

English

Type of outcome

Konferenční abstrakt

Field of Study

Genetics and molecular biology

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14110/02:00006182

Organization unit

Faculty of Medicine

Keywords in English

chronic heart failure; gene; polymorphism; TNF

Tags

Abstract

V originále

Pro-inflammatory peptides as TNFalpha, TNFbeta, as well as TNFalpha-converting enzyme (TACE) can be involved in the onset and/or progression of cardiovascular diseases. The aim of the study was to prove associations of three frequent polymorphisms in the genes (G(-308)A TNFalpha, NcoI TNFbeta and 2A/3A TACE) with chronic heart failure.

Links

MSM 141100002, plan (intention)
Name: Molekulární patofyziologie multigenních chorob
Investor: Ministry of Education, Youth and Sports of the CR, Molecular pathophysiology of multigene diseases